Well Principled is a startup that leverages AI to accelerate science-based product funnels by systematizing metascience through model-assisted selection. The company reframes product development as "learning to manipulate a mechanism" and facilitates enterprise-wide learning of identifying and disentangling mechanisms that lead to successful products. Its software enables science businesses to expedite time-to-market with fewer physical tests by encoding learnings in a simulation model trained on existing funnel testing data and a catalog of mechanisms from academic literature. The company has successfully applied its approach across diverse domains such as consumer science and hard science of electrochemistry for battery design and manufacturing. Well Principled's technology encapsulates core metascience learnings and consists of a universal mechanistic simulation modeling language, a system for learning mechanism parameters from data, and a system for building environmental simulators and business optimizers. Its "super suit" data architecture enables rapid customization of applications to accelerate science business product pipelines in any domain. Founded in 2018 and headquartered in the United States, Well Principled received a $50.00K grant investment on 28 October 2020 from Arch Grants. Their innovative approach and versatile technology position them as a promising player in the science business acceleration space.