Sage Science, Inc.

Sage Science, Inc. is a biotechnology company founded in 2005 and based in the United States. The company's mission is to revolutionize molecular biology workflows by providing high-precision, automated solutions for DNA size selection, essential for next-generation sequencing (NGS). With the slogan "DNA Size Selection for Next Gen Sequencing," Sage Science offers a portfolio of products designed to enhance accuracy, reproducibility, and throughput in molecular biology workflows. These products, including Pippin Prep, BluePippin, SageELF, and SageHLS, aim to improve data quality, reduce hands-on time, and optimize downstream results for life science and diagnostic labs. Sage Science's flagship product, SageHLS, introduces a novel approach to DNA target enrichment. It allows for the direct extraction of DNA from cells on the platform and utilizes Cas9 endonuclease/guide RNA complexes to excise and gather large targets from a genome. This process, known as CATCH (Cas9 assisted targeting of chromosomal segments), is particularly valuable for elucidating complex genomic structures such as pseudogenes, structural variants, and repetitive elements, with targets of up to 500MB in length. With a last investment of $874.00K from a Venture Round on 02 May 2014, Sage Science operates as a privately funded company and is headquartered at 500 Cummings Center in Beverly, MA, USA. The company's commitment to innovation and technology-driven solutions positions it as a promising player in the biotechnology industry.