Modifi Bio

Modifi Bio is a pioneering biotech startup founded in 2021 with the mission of using innovative DNA modification to combat cancer, as encapsulated in their slogan "Modifying DNA to Eradicate Cancer." The company is developing a groundbreaking oncology therapeutics platform that targets DNA defects in various cancer cells, aiming to revolutionize traditional oncology drug development. Their distinctive approach involves irreparably modifying tumor DNA while sparing healthy cells, achieved through a new class of small molecules directly targeting DNA, sidestepping the need to engage protein targets. This strategy has been successfully tested on a wide range of tumor types in both controlled environments and living organisms, affirming its promise. The founding team comprises esteemed scientists, clinicians, and biotech entrepreneurs. Their core technology, jointly discovered by Seth Herzon and Ranjit Bindra, brings in-depth expertise in synthetic chemistry, DNA repair, and translational research in oncology. Situated at the heart of New Haven, CT’s burgeoning biotech hub, Modifi Bio operates within the Elm City BioScience Center, a cutting-edge facility designed to support emerging biotechnology companies, conveniently located near the Yale School of Medicine. Notably, the startup recently secured a $4.30M seed round investment on 16 October 2023, with significant contributions from Connecticut Innovations, HighCape Partners, Ironwood Capital Connecticut, Pathway Bioventures, National Brain Tumor Society, Sontag Family Trust, and the BrightEdge Fund. This backing underscores investor confidence in Modifi Bio's potential to make a meaningful impact in the biotechnology and health and wellness industries, holding the promise of addressing unmet needs in cancer treatment.