Top Pharmaceutical Startups in United States (2025 Update)
Explore the best Pharmaceutical companies in United States. Discover high-growth startups and investment opportunities in our 2025 updated list.
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Explore Top Pharmaceutical Startups in United States featuring 2925 Companies
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Jasper Therapeutics | - | Jasper is a biotechnology company focused on targeting mast cells and stem cells... | Jasper Therapeutics is a biotechnology company on a mission to make safer and po... | - |
United States
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Redwood City | United States (HQ) | 2018 | Biotechnology, Health Care +2 | [email protected] |
1
Low
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72
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2.3K (-39%) | 1 year ago | Post Ipo Equity | 5 | 289.1M | 7475 | 5 months ago | |
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Castor | - | Delightful for patients, effortless for study teams, risk-free for sponsors. | At Castor, we believe in the power of clinical research and the power of technol... | - |
United States
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New York | United States (HQ) + 1 | 2011 | Health Care, Health and Wellness +1 | [email protected] |
1
Low
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252
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115.0K (-37%) | 3 years ago | Series B | 4 | 64.4M | 21059 | 5 months ago | |
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Narrativa Generative AI | - | Generative AI content automation platform | Accelerate the potential with Narrat... | Narrativa® is the leading generative AI technology company that offers a customi... | - |
United States
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Los Angeles | United States (HQ) + 3 | 2015 | AI, Analytics +6 | [email protected] |
1
Low
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18
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287 (-100%) | 3 years ago | Seed | 6 | 2.4M | 3312 | 11 months ago | |
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ApexQubit | - | ApexQubit is a biotechnology company that is harnessing frontier technologies fo... | ApexQubit is a biotechnology company that is harnessing frontier technologies fo... | - |
United States
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Berkeley | United States (HQ) | 2018 | B2B, Biotechnology +6 | [email protected] |
1
Low
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1
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557 | 4 years ago | Non Equity Assistance | 6 | 430.5K | 641 | 5 Jzj qwI | |
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Roivant | - | Reinventing Biopharma | Roivant aims to improve health by rapidly delivering innovative medicines and te... | - |
United States
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New York | United States (HQ) + 2 | 2014 | Biopharma, Biotechnology +2 | [email protected] |
1
Low
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256
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22.4K (2%) | 2 years ago | Post Ipo Equity | 7 | 2.5B | 29023 | 3 months ago | |
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Organon | - | Here for her health | Organon is a global healthcare company with a portfolio of therapies and product... | - |
United States
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Jersey City | United States (HQ) | 2020 | Health Care, Medical Devices +2 | - |
1
Low
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7087
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127.6K (-13%) | 1 year ago | Post Ipo Debt | 1 | 1.0B | 141777 | 5 months ago | |
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NewAmsterdam Pharma Corpo... | - | NewAmsterdam Pharma Corporation is a clinical-stage biopharma company creating t... | This page is intended for US audiences. Founded in 2019, NewAmsterdam Pharma Cor... | - |
United States
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Aventura | United States (HQ) | 2019 | Biotechnology, Life Sciences +1 | - |
1
Low
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64
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850 (-100%) | 1 year ago | Post Ipo Equity | 5 | 786.3M | 9566 | 5 months ago | |
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Xeno Biosciences | - | Gastric Bypass in a Pill | Xeno Biosciences is a biotechnology company pioneering a novel class of treatmen... | - |
United States
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Cambridge | United States (HQ) | 2015 | Biotechnology, Health Care +1 | - |
1
Low
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4
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99 (-100%) | 2 years ago | Debt Financing | 6 | 8.8M | 13571 | 2 ytf QIj | |
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InvivoSciences® Inc. | - | Discovery with Human touch | the InvivoSciences' mission is the research and development of engineered tissu... | - |
United States
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Madison | United States (HQ) | 2001 | Biotechnology, Health Care +2 | [email protected] |
1
Low
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4
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1.7K | 4 years ago | Non Equity Assistance | 2 | 700.0K | 508 | 12 years ago | |
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Kernal Biologics | - | KernalBio creates mRNA therapies that instruct specific cells on how to make the... | Kernal creates mRNA therapies to cure severe diseases including cancer. Our mRNA... | - |
United States
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Cambridge | United States (HQ) | 2016 | Biotechnology, Health and Wellness +1 | [email protected] |
1
Low
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16
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5.1K (6%) | 2 years ago | Series A | 5 | 25.0M | 3278 | 5 months ago | |
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Seven Bridges | - | Accelerate discovery with a complete bioinformatics ecosystem. | Seven Bridges is the industry-leading unified bioinformatics solutions company a... | - |
United States
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Boston | United States (HQ) + 5 | 2009 | Analytics, Cloud Infrastructure +4 | [email protected] |
1
Low
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171
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18.4K (-25%) | 4 years ago | Series C | 4 | 113.0M | 18969 | 4 months ago | |
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Alto Pharmacy | - | Alto is a digital pharmacy focused on helping people live healthier by making th... | Alto provides an easier, more efficient and more affordable pharmacy experience... | - |
United States
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San Francisco | United States (HQ) + 9 | 2015 | Health Care, Pharmaceutical | [email protected] |
1
Low
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812
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198.3K (-3%) | 6 months ago | Convertible Note | 11 | 680.0M | 24764 | 1 year ago | |
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Celeris Therapeutics | - | Better drugs faster with deep learning to design PROTACs and drug the undruggabl... | Celeris Therapeutics is going to solve the R&D shortcomings as the pioneer in AI... | - |
United States
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Menlo Park | United States (HQ) + 1 | 2021 | AI, Biotechnology +3 | [email protected] |
1
Low
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1
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933 | 2 years ago | Series Unknown | 5 | 16.5M | 5643 | 1 year ago | |
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Mixlab | - | The pet pharmacy humans are jealous of. | Mixlab is a modern veterinary pharmacy. | - |
United States
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New York | United States (HQ) + 1 | 2017 | Health Care, Pharmaceutical | [email protected] |
1
Low
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118
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143.6K (4%) | 1 year ago | Series A | 6 | 40.5M | 6384 | 5 months ago | |
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Tvardi Therapeutics | - | Breakthrough Medicines for Cancer, Chronic Inflammation & Fibrosis | Tvardi is a privately held, clinical-stage, biopharmaceutical company focused on... | - |
United States
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Houston | United States (HQ) | 2017 | Biotechnology, Health Care +1 | - |
1
Low
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18
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916 | 3 years ago | Series B | 2 | 81.4M | 2146 | 5 months ago | |
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Parimer Scientific | - | Parimer Scientific is a biotechnology innovation partner supporting development... | Parimer Scientific is an innovative biotechnology development partner. Owned and... | - |
United States
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Easley | United States (HQ) | 2018 | Biotechnology, Pharmaceutical | [email protected] |
1
Low
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8
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3.1K (41%) | 1 year ago | Grant | 1 | 50.0K | 535 | 8 months ago | |
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Prilenia | - | Dedicated to developing new treatments for neurodegenerative diseases and neurod... | Prilenia is a clinical-stage biotech company focused on developing novel treatme... | - |
United States
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Boston | United States (HQ) + 2 | 2018 | Biotechnology, Health Care +2 | [email protected] |
1
Low
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51
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5.5K (-52%) | 3 years ago | Series B | 2 | 105.5M | 6953 | 5 months ago | |
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AN2 Therapeutics | - | Developing therapies for rare, chronic, and serious infectious diseases | AN2 Therapeutics, Inc. is a biopharmaceutical company dedicated to developing th... | - |
United States
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Menlo Park | United States (HQ) | 2019 | Biotechnology, Health Care +1 | - |
1
Low
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37
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637 (-100%) | 1 year ago | Grant | 4 | 162.0M | 1775 | 5 months ago | |
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CymaBay Therapeutics | - | Dedicated to improving the lives of patients with liver diseases | We are a clinical-stage biopharmaceutical company focused on developing and prov... | - |
United States
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Newark | United States (HQ) | 1991 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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66
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2.0K (-57%) | 1 year ago | Post Ipo Equity | 15 | 854.2M | 13203 | 10 months ago | |
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Spiral Therapeutics | - | delivering therapies for inner ear disorders | We are a clinical stage company delivering therapies for inner ear disorders | - |
United States
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South San Francisco | United States (HQ) | 2016 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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10
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21 (-100%) | 1 year ago | Series Unknown | 5 | 18.5M | 1163 | 5 months ago | |
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Immuneering Corporation | - | Better Medicines Through Signaling Dynamics | Immuneering is a biopharmaceutical company with an emerging pipeline focused on... | - |
United States
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Cambridge | United States (HQ) + 2 | 2008 | Biotechnology, Pharmaceutical | [email protected] |
1
Low
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70
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2.8K (40%) | 2 years ago | Post Ipo Equity | 4 | 112.0M | 2722 | 5 months ago | |
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HiRO - Harvest Integrated... | - | Become the hero in innovative drug development | Harvest Integrated Research Organization (HiRO) is a globally oriented, innovati... | - |
United States
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Somerset | United States (HQ) | 2020 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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78
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1.5K (36%) | 3 years ago | Series A | 1 | 10.0M | 5875 | 5 months ago | |
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GrayBug | - | Saving Sight Through Transformative Science. | Graybug is a biopharmaceutical company focused on developing transformative medi... | - |
United States
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Redwood City | United States (HQ) + 1 | 2011 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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4
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994 (39%) | 5 years ago | Series C | 6 | 129.2M | 3661 | 9 XEE rsm | |
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I-Mab Biopharma | - | Bringing Transformational Medicines to Patients Through Innovation | I-Mab (NASDAQ: IMAB) is a U.S.-based, global biotech company, exclusively focuse... | - |
United States
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Rockville | United States (HQ) | 2016 | Biotechnology, Pharmaceutical | [email protected] |
1
Low
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134
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3.5K (17%) | 4 years ago | Post Ipo Equity | 5 | 815.0M | 4774 | 5 months ago | |
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Wherefour, Inc. | - | Wherefour is a modern and affordable ERP/traceability platform for companies tha... | Wherefour makes modern and affordable ERP and traceability software for companie... | - |
United States
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Petaluma | United States (HQ) | 2015 | Food and Beverage, Industrial +2 | - |
1
Low
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16
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7.3K (-9%) | 6 years ago | Series Unknown | 1 | 500.0K | 4240 | 5 months ago | |
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Imvax, Inc. | - | Imvax is a clinical-stage biotechnology company developing personalized, whole t... | Imvax is a clinical-stage biotechnology company developing personalized, whole t... | - |
United States
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Philadelphia | United States (HQ) | 2015 | Biotechnology, Health and Wellness +1 | [email protected] |
1
Low
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48
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2.3K (44%) | 1 year ago | Series Unknown | 5 | 224.7M | 3226 | 5 months ago | |
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Innovac Therapeutics | - | Bring Innovative mRNA Vaccines to Life | Innovac Therapeutics is a biotechnology company dedicated to developing innovati... | - |
United States
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Cambridge | United States (HQ) | 2022 | Biotechnology, Pharmaceutical +1 | [email protected] |
1
Low
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16
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706 (53%) | 1 year ago | Seed | 1 | 18.0M | 595 | 1 year ago | |
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Acreage Holdings | - | We deeply believe in the transformational power that cannabis has to heal and ch... | Headquartered in New York City, Acreage is a multi-state operator of cannabis c... | - |
United States
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New York | United States (HQ) | 2014 | Pharmaceutical | - |
1
Low
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236
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4.1K (-7%) | - | Post Ipo Equity | - | 629.7M | 34879 | 5 months ago | |
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Denison Pharmaceuticals | - | We are a premier contract development and manufacturing company serving OTC phar... | Denison is a leading provider of turnkey formulation, manufacturing and packagin... | - |
United States
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Lincoln | United States (HQ) | 1992 | Logistics, Manufacturing +1 | [email protected] |
1
Low
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95
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974 (30%) | 11 years ago | Private Equity | 1 | 8.0M | 3356 | 1 year ago | |
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GHX Lumere | Not active anymore | Lumere provides evidence-based data and accelerates your ability to optimize pat... | Lumere (formerly Procured Health) is an organization comprised of clinicians, re... | - |
United States
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Chicago | United States (HQ) | 2012 | Health Care, Medical Devices +2 | [email protected] |
-1
N/A
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741
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1.5K (36%) | 6 years ago | Corporate Round | 4 | 20.1M | 8086 | 1 year ago | |
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VYNE Therapeutics Inc. | - | For every therapeutic challenge, we question traditional assumptions and find be... | VYNE Therapeutics is a clinical-stage biopharmaceutical company focused on devel... | - |
United States
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Bridgewater | United States (HQ) | 2003 | Health Care, Health and Wellness +1 | [email protected] |
1
Low
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52
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1.7K (21%) | 1 year ago | Post Ipo Equity | 6 | 297.8M | 1936 | 6 months ago | |
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Avalyn Pharma | - | Targeted therapies for rare lung diseases | Avalyn is a clinical-stage biopharmaceutical company developing inhaled therapie... | - |
United States
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Cambridge | United States (HQ) | 2011 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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39
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2.1K (-55%) | 1 year ago | Series C | 3 | 272.5M | 4295 | 5 months ago | |
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Arcellx | - | We're a clinical-stage biotech company reimagining cell therapy through the deve... | We are a clinical-stage biotechnology company reimagining cell therapy through t... | - |
United States
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Redwood City | United States (HQ) | 2015 | Biopharma, Biotechnology +3 | [email protected] |
1
Low
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176
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12.5K (84%) | 1 year ago | Post Ipo Equity | 7 | 622.0M | 14684 | 5 months ago | |
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Orca Bio | - | Transforming allogeneic cell therapy for patients with cancer and autoimmune dis... | Orca Bio is a late-stage biotechnology company developing high-precision cell th... | - |
United States
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Menlo Park | United States (HQ) + 1 | 2016 | Health Care, Pharmaceutical | [email protected] |
1
Low
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170
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5.3K (6%) | 4 years ago | Series D | 3 | 192.0M | 14054 | 5 months ago | |
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BEKhealth | - | AI to find the right patients, right now. | Purpose-built for organizations conducting clinical trials and observational stu... | - |
United States
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Raleigh | United States (HQ) | 2020 | Health Care, IT +2 | [email protected] |
1
Low
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28
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1.8K (6%) | 1 year ago | Series Unknown | 3 | 11.1M | 3177 | 1 year ago | |
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Spine BioPharma | - | Back Pain Relief has a New Name! | Patients around the world are struggling with debilitating back pain, trying to... | - |
United States
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New York | United States (HQ) | 2015 | Biotechnology, Pharmaceutical | [email protected] |
1
Low
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14
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2.0K | 1 year ago | Series Unknown | 4 | 38.3M | 935 | 5 months ago | |
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Elanco | - | Making life better for animals, makes life better. | At Elanco, we work to improve the health of animals through innovative products... | - |
United States
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Greenfield | United States (HQ) | 1954 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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8471
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1.0M (-29%) | 1 year ago | Post Ipo Equity | 2 | 252.9M | 309794 | 6 months ago | |
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Reverse Medical Corporati... | Not active anymore | A commercial-stage medical device company dedicated to restoring blood flow in p... | Reverse Medical is a commercial-stage medical device company focused on revascul... | - |
United States
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Irvine | United States (HQ) | 2007 | Biotechnology, Health Care +1 | - |
-1
N/A
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8
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915 | 15 years ago | Series B | 3 | 18.5M | 4 | 9 kkV U9L | |
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ARIZ Precision Medicine | - | Targeting Cancer at the Root Cause | ARIZ Precision Medicine is pre-clinical stage company aiming to selectively targ... | - |
United States
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Davis | United States (HQ) | 2015 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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3
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722 (3%) | 3 years ago | Convertible Note | 3 | 2.7M | 508 | 6 months ago | |
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DocStation | - | Empowering pharmacies to transform into clinical care destinations through our m... | DocStation helps health plans and pharmacies collaborate to improve outcomes and... | - |
United States
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Austin | United States (HQ) | 2017 | Digital Health, Health Care +2 | [email protected] |
1
Low
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20
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4.8K (26%) | 1 year ago | Seed | 3 | 3.4M | 2968 | 5 months ago |