Top Life Sciences Startups in United States (2025 Update)
Explore the best Life Sciences companies in United States. Discover high-growth startups and investment opportunities in our 2025 updated list.
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Explore Top Life Sciences Startups in United States featuring 1325 Companies
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Cultiply | - | Cultiply uses bioreactors to improve industrial fermentation, reducing costs and... | Cultiply specializes in biotechnology and aims to enhance and innovate industria... | - |
United States
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Seville | United States (HQ) | 2018 | Biotechnology, Life Sciences +1 | [email protected] |
1
Low
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313
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98 | 4 years ago | Debt Financing | 1 | 40.0K | 4162 | 1 year ago | |
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NodThera | - | Treating chronic disease by targeting inflammation at its source | NodThera is developing a new class of potent and highly selective NLRP3 inflamma... | - |
United States
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Philadelphia | United States (HQ) + 2 | 2016 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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25
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1.3K (-24%) | 5 years ago | Series B | 2 | 95.0M | 3745 | 5 months ago | |
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Narrativa Generative AI | - | Generative AI content automation platform | Accelerate the potential with Narrat... | Narrativa® is the leading generative AI technology company that offers a customi... | - |
United States
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Los Angeles | United States (HQ) + 3 | 2015 | AI, Analytics +6 | [email protected] |
1
Low
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18
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823 (-100%) | 3 years ago | Seed | 6 | 2.4M | 3312 | 11 months ago | |
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Totient - Part of Absci | - | Artificial Intelligence for Drug Discovery | Totient is an AI-driven biotechnology company leveraging tertiary lymphoid struc... | - |
United States
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Cambridge | United States (HQ) + 2 | 2017 | AI, Biotechnology +2 | [email protected] |
1
Low
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5
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238 | 4 years ago | Series Unknown | 2 | 10.0M | 1103 | 7 gOd sLP | |
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ApexQubit | - | ApexQubit is a biotechnology company that is harnessing frontier technologies fo... | ApexQubit is a biotechnology company that is harnessing frontier technologies fo... | - |
United States
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Berkeley | United States (HQ) | 2018 | B2B, Biotechnology +6 | [email protected] |
1
Low
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1
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762 | 4 years ago | Non Equity Assistance | 6 | 430.5K | 641 | 9 OCy 39u | |
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NewAmsterdam Pharma Corpo... | - | NewAmsterdam Pharma Corporation is a clinical-stage biopharma company creating t... | This page is intended for US audiences. Founded in 2019, NewAmsterdam Pharma Cor... | - |
United States
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Aventura | United States (HQ) | 2019 | Biotechnology, Life Sciences +1 | - |
1
Low
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64
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776 (-100%) | 1 year ago | Post Ipo Equity | 5 | 786.3M | 9566 | 5 months ago | |
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Biosplice Therapeutics | - | Restore health by delivering first-in-class therapies that harness alternative s... | Biosplice is developing first-in-class, small-molecule therapeutics based on pio... | - |
United States
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San Diego | United States (HQ) | 2008 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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37
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2.4K | 1 year ago | Grant | 6 | 778.0M | 3967 | 8 months ago | |
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Correlia Biosystems | - | Next-gen instruments for quantitative protein measurement (We are hiring, check... | Correlia Biosystems develops innovative microscale tools that accelerate the rat... | - |
United States
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Berkeley | United States (HQ) | 2013 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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11
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264 | 4 years ago | Series Unknown | 10 | 10.7M | 2217 | 11 months ago | |
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Pera Labs | - | Our goal to Inspire, Innovate, Impact by Developing Smart Solutions for Animal &... | At Pera Labs, we develop digiceuticals and ai-powered solutions for difficult he... | - |
United States
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Philadelphia | United States (HQ) + 1 | 2019 | AI, Health Care +3 | [email protected] |
1
Low
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4
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557 | 1 year ago | Seed | 3 | 1.3M | 1551 | 1 year ago | |
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InvivoSciences® Inc. | - | Discovery with Human touch | the InvivoSciences' mission is the research and development of engineered tissu... | - |
United States
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Madison | United States (HQ) | 2001 | Biotechnology, Health Care +2 | [email protected] |
1
Low
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4
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1.7K | 4 years ago | Non Equity Assistance | 2 | 700.0K | 508 | 12 years ago | |
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Celeris Therapeutics | - | Better drugs faster with deep learning to design PROTACs and drug the undruggabl... | Celeris Therapeutics is going to solve the R&D shortcomings as the pioneer in AI... | - |
United States
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Menlo Park | United States (HQ) + 1 | 2021 | AI, Biotechnology +3 | [email protected] |
1
Low
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1
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657 | 2 years ago | Series Unknown | 5 | 16.5M | 5643 | 1 year ago | |
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Prilenia | - | Dedicated to developing new treatments for neurodegenerative diseases and neurod... | Prilenia is a clinical-stage biotech company focused on developing novel treatme... | - |
United States
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Boston | United States (HQ) + 2 | 2018 | Biotechnology, Health Care +2 | [email protected] |
1
Low
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51
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5.5K (-52%) | 3 years ago | Series B | 2 | 105.5M | 6953 | 5 months ago | |
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SPARK Neuro | - | 40% of dementia is not diagnosed. We partner with healthcare providers and payer... | SPARK Neuro's mission is to make brain health assessments a standard part of car... | - |
United States
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Los Angeles | United States (HQ) | 2017 | Health Care, Life Sciences | [email protected] |
1
Low
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26
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1.5K (50%) | 2 years ago | Series A | 2 | 23.5M | 2526 | 6 months ago | |
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Filtricine, Inc. | - | Treating Cancer and Metabolic Diseases with Food | Filtricine develops and commercializes food products that can treat cancer and m... | - |
United States
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Sunnyvale | United States (HQ) | 2017 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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5
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980 (16%) | 2 years ago | Seed | 4 | 5.3M | 398 | 10 months ago | |
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Parse Biosciences | - | Scalable Single Cell Sequencing Without the Instrument | Parse Biosciences is a global life sciences company whose mission is to accelera... | - |
United States
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Seattle | United States (HQ) | 2018 | Biotechnology, Life Sciences +1 | [email protected] |
1
Low
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132
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37.1K (-32%) | 1 year ago | Series C | 6 | 100.0M | 17245 | 5 months ago | |
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Via Nova Therapeutics | - | An antiviral startup focusing on acute and subacute viral infections for which t... | Via Nova Therapeutics’ mission is to discover and develop safe and effective new... | - |
United States
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Berkeley | United States (HQ) | 2021 | Biotechnology, Health and Wellness +1 | - |
1
Low
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3
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259 (-76%) | 3 years ago | Series Unknown | 2 | 25.0M | 298 | 1 year ago | |
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Eigen Therapeutics | - | We help targeted therapies hit their mark. | Eigen Therapeutics is a biotechnology company on a mission to make therapies tha... | - |
United States
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Redwood City | United States (HQ) | 2021 | Biotechnology, Life Sciences | - |
1
Low
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10
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637 (-100%) | 1 year ago | Seed | 4 | 7.0M | 673 | 2 years ago | |
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QuantumCyte, Inc. | - | NextGen Microdissection Platform | QuantumCyte is a technology platform company that developed an ‘in-situ lysis’ m... | - |
United States
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Sunnyvale | United States (HQ) | 2013 | Biotechnology, Life Sciences | [email protected] |
1
Low
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10
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454 (-20%) | 1 year ago | Series A | 6 | 1.1M | 814 | 6 months ago | |
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Element Biosciences | - | Opening the world of biology to new possibilities | Element Biosciences is a pioneering life science company democratizing access to... | - |
United States
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San Diego | United States (HQ) + 1 | 2017 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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386
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37.1K (-54%) | 10 months ago | Series D | 5 | 678.0M | 39634 | 5 months ago | |
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LabFellows | - | Do More Science. |
The LabOps Platform built for Science as a Business. LabFellows was created by... |
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United States
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La Jolla | United States (HQ) | 2014 | Biotechnology, Life Sciences +1 | [email protected] |
1
Low
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5
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1.3K (30%) | 7 years ago | Seed | 5 | 350.0K | 846 | 5 months ago | |
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Twist Bioscience | - | Synthetic DNA for Health & Sustainability | Twist Bioscience is a synthetic biology company based in South San Francisco, Ca... | - |
United States
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South San Francisco | United States (HQ) + 3 | 2013 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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1077
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121.9K (-4%) | 3 years ago | Post Ipo Equity | 10 | 553.1M | 150207 | 5 months ago | |
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Resilient Lifescience | - | Combating overdose with intelligent drug discovery | Resilient Lifescience is a Pittsburgh-based startup building a wearable medical... | - |
United States
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Pittsburgh | United States (HQ) | 2022 | Hardware, Health and Wellness +1 | - |
1
Low
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4
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1.6K (198%) | 1 year ago | Pre Seed | 3 | 625.0K | 1614 | 7 months ago | |
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Galera Therapeutics, Inc. | - | Transforming the science and treatment of cancer | Galera Therapeutics is focused on developing and commercializing a pipeline of n... | - |
United States
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Malvern | United States (HQ) + 1 | 2009 | Biotechnology, Health and Wellness +1 | - |
1
Low
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15
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1.9K (-30%) | 2 years ago | Post Ipo Equity | 12 | 178.6M | 9408 | 1 year ago | |
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Avadim Holdings, Inc. | - | A life sciences company changing lives and transforming communities with advance... | Based in Asheville, North Carolina (USA), Avadim Health, Inc., is a rapidly grow... | - |
United States
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Asheville | United States (HQ) | 2007 | Biotechnology, Consumer Goods +2 | [email protected] |
1
Low
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85
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114 (-83%) | 5 years ago | Series D | 12 | 99.6M | 1757 | 5 months ago | |
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Prapela | - | Prapela is a breakthrough noninvasive stimulation therapy that naturally improve... | Prapela is a breakthrough noninvasive stimulation therapy that naturally improve... | - |
United States
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Biddeford | United States (HQ) | 2017 | Health Care, Health and Wellness +1 | [email protected] |
1
Low
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4
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785 | 1 year ago | Grant | 15 | 8.2M | 650 | 6 months ago | |
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HTG Molecular Diagnostics | - | HTG is focused on advancing precision medicine | HTG is accelerating precision medicine from diagnosis to treatment by harnessing... | - |
United States
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Tucson | United States (HQ) | 1997 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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33
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4.5K (73%) | 2 years ago | Post Ipo Equity | 14 | 106.5M | 4906 | 1 year ago | |
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Enable Injections, Inc. | - | Enable's body-worn enFuse® drug delivery technology delivers large volumes (5 -... | Cincinnati-based Enable Injections is a global healthcare innovation company dev... | - |
United States
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Cincinnati | United States (HQ) | 2010 | Health Care, Life Sciences +2 | [email protected] |
1
Low
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189
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532 (-100%) | 3 years ago | Series C | 8 | 347.0M | 6689 | 5 months ago | |
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GreenLight Biosciences | - | A mission-driven biotech using the power of RNA to tackle some of humanity's gre... | GreenLight Biosciences is a mission-driven public-benefit corporation using the... | - |
United States
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Medford | United States (HQ) + 2 | 2008 | Agriculture, Biotechnology +2 | [email protected] |
1
Low
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160
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5.7K (10%) | 2 years ago | Post Ipo Equity | 10 | 449.5M | 18454 | 1 year ago | |
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Lightning MD | - | The ideal billing and scheduling solution for any practice | Lightning MD is a cloud-based medical billing software built by medical professi... | - |
United States
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Palm Desert | United States (HQ) | 2016 | Health Care, Health and Wellness +1 | [email protected] |
1
Low
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2
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577 | 4 years ago | Non Equity Assistance | 2 | 100.0K | 1095 | 5 x1l h9o | |
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Deep Lens (acquired by Pa... | - | Accelerating clinical trial matching in oncology | Deep Lens is a digital healthcare company focused on enabling faster recruitment... | - |
United States
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Columbus | United States (HQ) | 2017 | AI, Health Care +2 | - |
1
Low
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5
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26 | 6 years ago | Series A | 2 | 17.2M | 3663 | 7 qgT cZ2 | |
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Arcellx | - | We're a clinical-stage biotech company reimagining cell therapy through the deve... | We are a clinical-stage biotechnology company reimagining cell therapy through t... | - |
United States
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Redwood City | United States (HQ) | 2015 | Biopharma, Biotechnology +3 | [email protected] |
1
Low
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176
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12.5K (84%) | 1 year ago | Post Ipo Equity | 7 | 622.0M | 14684 | 5 months ago | |
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Ossium Health | - | The Greatest Wealth is Health® | Our mission is to improve the health, vitality, and longevity of human beings th... | - |
United States
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San Francisco | United States (HQ) + 1 | 2016 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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93
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1.5K (-6%) | 1 year ago | Series C | 6 | 128.9M | 3183 | 5 months ago | |
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Prolacta Bioscience | - | Advancing the science of human millk | Prolacta Bioscience is a privately-held life sciences company dedicated to Advan... | - |
United States
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City Of Industry | United States (HQ) + 1 | 1999 | Biotechnology, Health Care +2 | [email protected] |
1
Low
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310
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38.7K | 7 years ago | Series Unknown | 8 | 78.0M | 6468 | 5 months ago | |
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Intuitive Biosciences | - | Supporting biomedical research through serological testing services and kits. | Intuitive Biosciences has been supporting biomedical research since 2012 by prov... | - |
United States
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Madison | United States (HQ) | 2012 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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9
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1.7K (169%) | 11 months ago | Grant | 5 | 2.5M | 779 | 10 MBm sW6 | |
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IconOVir Bio | - | Pushing the envelope: Our mission is to cure cancer and restore life to every pa... | IconOVir Bio is a preclinical-stage biotechnology company pioneering the next ge... | - |
United States
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San Diego | United States (HQ) | 2018 | Biotechnology, Life Sciences | [email protected] |
1
Low
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17
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2.0K | 4 years ago | Series A | 1 | 77.0M | 2247 | 1 year ago | |
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Abilita Therapeutics, Inc... | - | Redefining the druggable landscape for membrane protein targets | Abilita Therapeutics is a biotechnology company focused on redefining the drugga... | - |
United States
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San Diego | United States (HQ) | 2014 | Biotechnology, Life Sciences | [email protected] |
1
Low
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19
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1.2K (48%) | 2 years ago | Series Unknown | 1 | 7.5M | 2253 | 5 months ago | |
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Elysium Health | - | The company that believes everyone should benefit directly from compelling scien... | Elysium Health’s mission is to solve the biggest challenges in health with scien... | - |
United States
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New York | United States (HQ) | 2014 | Health Care, Health and Wellness +2 | [email protected] |
1
Low
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82
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92.4K (14%) | 3 years ago | Series C | 8 | 71.2M | 4831 | 5 cCl gfe | |
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ELEGEN | - | Unlock the promise of synthetic biology by accelerating the Design-Build-Test-Le... | We are now at the dawn of the synthetic biology revolution, which will spawn new... | - |
United States
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San Carlos | United States (HQ) | 2017 | Biotechnology, Health Care +1 | - |
1
Low
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93
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14.5K (-1%) | 1 year ago | Series B | 2 | 35.0M | 5666 | 5 months ago | |
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Ganymede | - | Ganymede is the modern cloud data platform for the life sciences and manufacturi... | Ganymede liberates your data by connecting your instruments, your LIMS, and your... | - |
United States
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Palo Alto | United States (HQ) | 2022 | Biopharma, Enterprise Software +1 | [email protected] |
1
Low
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56
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998 (-100%) | 2 years ago | Series A | 2 | 15.7M | 9630 | 5 months ago | |
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Immusoft | - | Cell therapy company dedicated to improving the lives of patients with rare dise... | Immusoft is a cell therapy company focused on developing novel therapies for rar... | - |
United States
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Seattle | United States (HQ) + 1 | 2009 | Biotechnology, Health Care +2 | [email protected] |
1
Low
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23
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1.3K (-28%) | 2 years ago | Grant | 12 | 49.3M | 2778 | 5 months ago |