Top IT Infrastructure Startups in United States (2025 Update)
Explore the best IT Infrastructure companies in United States. Discover high-growth startups and investment opportunities in our 2025 updated list.
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Explore Top IT Infrastructure Startups in United States featuring 822 Companies
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Fizbot | - | Become a digital realtor. | We believe that buying, selling, or investing in real estate seriously matters a... | - |
United States
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Istanbul | United States (HQ) + 1 | 2020 | Automation, IT Infrastructure +3 | [email protected] |
1
Low
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19
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16.7K (-60%) | 2 years ago | Convertible Note | 3 | 1.1M | 2066 | 5 months ago | |
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IP Fabric | - | Automated Network Assurance Platform | Do you know your network end-to-end? We d... | IP Fabric’s Automated Network Assurance Platform helps companies empower their n... | - |
United States
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New York | United States (HQ) + 1 | 2015 | Analytics, Big Data +3 | [email protected] |
1
Low
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131
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16.9K | 1 year ago | Series B | 5 | 27.9M | 6631 | 2 months ago | |
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Nightingale Security | - | Automating Physical Security. | Nightingale Security is a pioneer in Robotic Aerial Security (RAS). Our intellig... | - |
United States
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Newark | United States (HQ) | 2014 | Cyber Security, Drones +3 | [email protected] |
1
Low
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32
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4.0K (-44%) | 2 years ago | Private Equity | 7 | 24.8M | 2407 | 8 months ago | |
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Vertiv | - | Vertiv designs, builds and services mission-critical technologies. | Vertiv (NYSE: VRT) brings together hardware, software, analytics and ongoing ser... | - |
United States
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Columbus | United States (HQ) + 5 | 2016 | Data Analytics, IT Infrastructure +2 | [email protected] |
1
Low
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14650
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772.8K (2%) | 2 years ago | Post Ipo Equity | 2 | 1.2B | 476234 | 7 months ago | |
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TenaFe Inc | - | Innovation. Quality. Trust. | TenaFe, Inc. is a solid-state drive (SSD) controller startup that brings innovat... | - |
United States
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Campbell | United States (HQ) | 2019 | Data Analytics, IT Infrastructure +1 | [email protected] |
1
Low
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43
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380 (-95%) | 3 years ago | Series Unknown | 3 | 87.0M | 538 | 9 months ago | |
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Wellvana | - | We help doctors deliver life-changing healthcare. | The healthcare system isn’t designed for health. We’re designed to change that.... | - |
United States
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Nashville | United States (HQ) | 2018 | Health Care, IT Infrastructure | [email protected] |
1
Low
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149
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3.3K (18%) | 2 years ago | Series B | 2 | 88.5M | 7089 | 5 months ago | |
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Alpha Grid | - | Accelerating charging infrastructure for a decarbonized future. | The clean energy transition requires unprecedented investment in the grid and im... | - |
United States
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Palo Alto | United States (HQ) | 2022 | Analytics, IT Infrastructure +1 | - |
1
Low
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8
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1.0K (-50%) | 1 year ago | Pre Seed | 1 | 2.5M | 6008 | 1 year ago | |
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NetApp Instaclustr | - | Intelligent, open source application data infrastructure for the enterprise | Instaclustr helps companies unlock the true power of open source technologies th... | - |
United States
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Redwood City | United States (HQ) + 2 | 2013 | Analytics, Big Data +7 | [email protected] |
1
Low
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106
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71.2K (-13%) | 6 years ago | Private Equity | 4 | 22.2M | 7574 | 8 months ago | |
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Mio | - | Mio powers cross-platform communication across Google Chat, Microsoft Teams, Sla... | Mio is a secure middleware that unlocks cross-platform messaging, file sharing,... | - |
United States
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Austin | United States (HQ) + 1 | 2015 | IT Infrastructure, Messaging +1 | [email protected] |
1
Low
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103
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120.7K (-3%) | 3 years ago | Series A | 4 | 17.0M | 3330 | 1 year ago | |
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Jolt AI | - | Teams ship code faster with Jolt | Jolt is an AI codegen tool that takes a coding task, generates an editable file-... | - |
United States
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San Francisco | United States (HQ) | 2022 | Cloud Infrastructure, Developer Tools +2 | [email protected] |
1
Low
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9
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1.5K (7%) | 2 years ago | Pre Seed | 1 | 2.3M | 649 | 7 months ago | |
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Mechanical Orchard | - | We take the risk out of modernizing your most critical legacy applications. | Mechanical Orchard is an AI-native technology company that de-risks the process... | - |
United States
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San Francisco | United States (HQ) + 1 | 2022 | API, Cloud Infrastructure +2 | [email protected] |
1
Low
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103
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9.8K (-1%) | 9 months ago | Series A | 3 | 31.0M | 4652 | 9 months ago | |
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Locusview | - | A comprehensive solution for managing utility construction work from planning th... | Locusview’s Digital Construction Management (#DCM) platform enables utilities to... | - |
United States
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Chicago | United States (HQ) | 2014 | Energy, IT Infrastructure +2 | [email protected] |
1
Low
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148
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1.6K | 4 years ago | Series A | 3 | 77.4M | 13612 | 7 months ago | |
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Fusion Connect | - | Removing Complexity is Simply What We Do | Fusion Connect, an industry leading cloud communications provider, removes compl... | - |
United States
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Atlanta | United States (HQ) | 1997 | IT Infrastructure, Information Technology +2 | [email protected] |
1
Low
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1605
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228.2K (-15%) | 1 year ago | Post Ipo Debt | 7 | 75.2M | 9102 | 5 months ago | |
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Mirantis | - | Strategic open source infrastructure for containers and virtual machines. | We provide strategic open source infrastructure to give our customers complete c... | - |
United States
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Campbell | United States (HQ) + 18 | 1999 | Computing, DevOps +3 | [email protected] |
1
Low
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589
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410 (-100%) | 1 year ago | Debt Financing | 6 | 240.0M | 70436 | 5 months ago | |
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5 Lakes Institute | - | A curated network that drives and amplifies tech-enabled GDP growth in the Midwe... | 5 Lakes Institute is a curated network of entrepreneurs, research organizations,... | - |
United States
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Milwaukee | United States (HQ) | 2007 | Computing, IT Infrastructure +1 | [email protected] |
1
Low
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7
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1.1K (15%) | 2 years ago | Grant | 1 | 175.0K | 139 | 5 KYI pr2 | |
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Tetrate | - | Tetrate solves application networking and security, enabling innovation with spe... | Tetrate provides the world’s leading Application Networking and Security Platfor... | - |
United States
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Milpitas | United States (HQ) | 2018 | API, Applications +5 | [email protected] |
1
Low
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121
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30.0K (-37%) | 4 years ago | Series B | 2 | 52.5M | 7263 | 5 months ago | |
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Mascotte | Client & Opera... | - | Mascotte is the virtual front-desk & back-office operations team for modern vet... | Mascotte handles your client communications & admin tasks in a way that’s tailor... | - |
United States
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Miami | United States (HQ) | 2023 | IT Infrastructure | - |
1
Low
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8
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1.8K (-25%) | 1 year ago | Pre Seed | 1 | 1.2M | 682 | 6 months ago | |
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Corsha | - | Security, visibility and control for API communications through fully-automated... | Corsha's Identity Provider for Machines offers a cutting-edge solution for advan... | - |
United States
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Vienna | United States (HQ) | 2018 | Automation, Cloud Infrastructure +5 | [email protected] |
1
Low
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39
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3.7K (-60%) | 1 year ago | Grant | 6 | 16.7M | 3483 | 5 months ago | |
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Kubiya.ai | - | Empowering the future of technical operations through a digital workforce of AI... | Accelerate time-to-automation by delegating routine tasks to AI Teammates, avail... | - |
United States
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San Jose | United States (HQ) | 2022 | AI, Cloud Infrastructure +2 | - |
1
Low
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26
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15.5K (-39%) | 9 months ago | Seed | 3 | 12.0M | 9071 | 5 months ago | |
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Story | - | Story is building open IP infrastructure for the internet era. | Story is building open IP infrastructure to grow the creativity of the internet... | - |
United States
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San Francisco | United States (HQ) | 2022 | Blockchain, IT Infrastructure +3 | - |
1
Low
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114
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23.2K (25%) | 1 year ago | Series A | 2 | 54.3M | 5799 | 6 months ago | |
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Fleet Device Management | - | Open-source device management for IT and security teams with thousands of laptop... | Open-source device management for IT and security teams with thousands of laptop... | - |
United States
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San Francisco | United States (HQ) | 2020 | Cyber Security, IT +1 | - |
1
Low
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58
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22.2K (-1%) | 3 years ago | Series A | 3 | 25.0M | 3832 | 5 months ago | |
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Teren, Inc. | - | Make the Leap from Risk to Resilience. | Founded in 2021, Teren helps businesses and communities manage environmental thr... | - |
United States
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Lakewood | United States (HQ) | 2021 | Analytics, IT Infrastructure | [email protected] |
1
Low
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23
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2.1K (40%) | 1 year ago | Debt Financing | 3 | 12.1M | 1948 | 5 months ago | |
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ModelOp | - | ModelOp is the leading AI Governance software that helps global enterprises gove... | ModelOp is the leading AI Governance software for enterprises and helps safeguar... | - |
United States
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Chicago | United States (HQ) | 2016 | AI, Analytics +4 | [email protected] |
1
Low
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40
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5.4K (-33%) | 5 years ago | Series A | 2 | 6.0M | 3816 | 5 months ago | |
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Meter | - | Internet infrastructure for the enterprise. | Meter provides internet infrastructure for businesses. Headquartered in San Fran... | - |
United States
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San Francisco | United States (HQ) | 2015 | IT Infrastructure, Information Technology +1 | [email protected] |
1
Low
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100
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51.4K (34%) | 1 year ago | Series B | 4 | 85.0M | 5006 | 6 months ago | |
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HYCU, Inc. | - | HYCU’s mission is to build a safer world by harmonizing protection and visibilit... | At HYCU, we believe that every business should be safe. Our mission is to build... | - |
United States
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Boston | United States (HQ) | 2018 | Cloud Infrastructure, IT +1 | [email protected] |
1
Low
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262
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52.9K (41%) | 2 years ago | Series B | 3 | 140.5M | 16208 | 5 months ago | |
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Scale Computing | - | A market leader in edge computing, virtualization and hyperconverged solutions. | Scale Computing is a leader in edge computing, virtualization, and hyperconverge... | - |
United States
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Indianapolis | United States (HQ) + 1 | 2007 | Computing, Data Analytics +2 | [email protected] |
1
Low
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221
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47.6K (77%) | 2 years ago | Series Unknown | 11 | 202.8M | 20661 | 5 months ago | |
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ZBD | - | Powering real economies in virtual worlds. Disclosure: http://zbd.gg/z/terms | We're creating new ways to build the Bitcoin economy with the power of Lightning... | - |
United States
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Hoboken | United States (HQ) | 2019 | Crypto, IT Infrastructure +1 | - |
1
Low
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78
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728.5K (10%) | 2 years ago | Series B | 3 | 46.5M | 3942 | 5 months ago | |
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DuploCloud | - | DevOps automation platform to streamline infrastructure provisioning, providing... | DuploCloud offers an end-to-end DevOps software platform for dev teams that don’... | - |
United States
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San Jose | United States (HQ) + 1 | 2018 | API, Computing +3 | [email protected] |
1
Low
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138
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39.6K (-10%) | 1 year ago | Series B | 3 | 49.5M | 10705 | 5 months ago | |
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Moogsoft | - | Moogsoft is an AIOps incident management platform for engineering teams responsi... | Moogsoft is an AIOps incident management platform for engineering teams responsi... | - |
United States
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San Francisco | United States (HQ) + 1 | 2012 | Analytics, Enterprise Software +3 | [email protected] |
1
Low
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30
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24.0K (8%) | 4 years ago | Series Unknown | 5 | 112.9M | 11119 | 1 year ago | |
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RudderStack | - | The Warehouse Native CDP | RudderStack is the only customer data platform built from the ground up for data... | - |
United States
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San Francisco | United States (HQ) | 2019 | Analytics, Data Analytics +2 | [email protected] |
1
Low
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164
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140.7K (8%) | 3 years ago | Series B | 3 | 82.0M | 57107 | 8 months ago | |
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Ascent Platform | - | Every application, every form, one experience. | Imagine a beautiful and consistent experience for every digital touchpoint acros... | - |
United States
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New York | United States (HQ) | 2022 | Data Analytics, IT Infrastructure +1 | - |
1
Low
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23
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1.1K (10%) | 1 year ago | Series Unknown | 3 | 5.4M | 986 | 5 months ago | |
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iXsystems | - | Enterprise Storage and Servers, Driven by Open Source | iX is an Open Source pioneer and the company behind TrueNAS®, the world’s most d... | - |
United States
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San Jose | United States (HQ) | 2002 | IT, IT Infrastructure +1 | [email protected] |
1
Low
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190
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419 (-100%) | 15 years ago | Series Unknown | 1 | 2.0M | 9211 | 5 months ago | |
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LogicMonitor | - | At LogicMonitor, we expand what’s possible for businesses by advancing the techn... | We’re in the midst of an information revolution, and monitoring is at the center... | - |
United States
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Santa Barbara | United States (HQ) + 5 | 2007 | Analytics, Cloud Infrastructure +5 | [email protected] |
1
Low
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1163
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566.5K (-31%) | 3 years ago | Debt Financing | 6 | 142.9M | 91045 | 6 months ago | |
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Device42, A Freshworks Co... | - | Hybrid IT Discovery & Dependency Mapping Platform | With customers across 70+ countries, organizations of all sizes rely on Device42... | - |
United States
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West Haven | United States (HQ) | 2010 | Data Analytics, DevOps +2 | [email protected] |
1
Low
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122
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69.6K | 6 years ago | Series A | 4 | 38.5M | 6141 | 5 months ago | |
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Platform9 | - | A better way to go cloud native. |
Platform9 is a leader in simplifying enterprise private clouds. Our flagship pr... |
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United States
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Mountain View | United States (HQ) + 1 | 2013 | Computing, Enterprise Software +2 | [email protected] |
1
Low
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117
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64.6K (-10%) | 2 years ago | Series Unknown | 8 | 100.0M | 50047 | 5 months ago | |
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Stel Life | - | Simplifying device connectivity for patients, care teams, and digital health |
Learn more: Website: https://www.stel.life Twitter: https://twitter.com/VitalsH... |
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United States
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Philadelphia | United States (HQ) | 2016 | Digital Health, Health Care +2 | [email protected] |
1
Low
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17
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2.4K (140%) | 4 years ago | Pre Seed | 3 | 2.8M | 1168 | 7 months ago | |
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Okta | 5 days ago mentioned on Cnbc. (View) | The World's Identity Company | Okta gives you a neutral, powerful and extensible platform that puts identity at... | - |
United States
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San Francisco | United States (HQ) + 10 | 2009 | Analytics, Enterprise Software +3 | [email protected] |
1
Low
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8073
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177.1M (6%) | 4 years ago | Post Ipo Equity | 9 | 1.2B | 447828 | 5 months ago | |
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Entitle - a BeyondTrust c... | - | Automated least privilege access for critical cloud applications. | Entitle provides a seamless way to grant employees granular and just-in-time acc... | - |
United States
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New York | United States (HQ) + 1 | 2021 | Analytics, Cloud Infrastructure +4 | [email protected] |
1
Low
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35
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13.4K (-29%) | 2 years ago | Seed | 1 | 15.0M | 3551 | 6 months ago | |
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Kubecost | - | With our open source and enterprise monitoring tools, we empower teams to optimi... | Backed by leading VCs and software executives and founded by ex-Google cloud eng... | - |
United States
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San Francisco | United States (HQ) | 2019 | API, IT Infrastructure +1 | [email protected] |
1
Low
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56
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74.4K (-19%) | 3 years ago | Series A | 2 | 30.5M | 7228 | 6 months ago | |
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KeyCaliber | - | Bridging the gap between cybersecurity operations and business operations | KeyCaliber’s platform enables organizations to prioritize what matters most to r... | - |
United States
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Arlington | United States (HQ) | 2020 | Cloud Infrastructure, Cyber Security +2 | [email protected] |
1
Low
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10
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469 (-57%) | 3 years ago | Seed | 1 | 2.6M | 621 | 5 months ago |