Top Health and Wellness Startups in United States (2025 Update)
Explore the best Health and Wellness companies in United States. Discover high-growth startups and investment opportunities in our 2025 updated list.
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Explore Top Health and Wellness Startups in United States featuring 9682 Companies
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AYO by Novalogy | - | AYO: Sleep Better, Boost Energy, Improve Wellbeing. | Novalogy's mission is helping millions upgrade their health in order to lead hap... | - |
United States
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Claymont | United States (HQ) + 2 | 2015 | Hardware, Health Care +1 | [email protected] |
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8
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13.6K (74%) | 4 years ago | Seed | 3 | 523.8K | 671 | 6 months ago | |
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Jasper Therapeutics | - | Jasper is a biotechnology company focused on targeting mast cells and stem cells... | Jasper Therapeutics is a biotechnology company on a mission to make safer and po... | - |
United States
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Redwood City | United States (HQ) | 2018 | Biotechnology, Health Care +2 | [email protected] |
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72
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2.3K (-39%) | 1 year ago | Post Ipo Equity | 5 | 289.1M | 7475 | 5 months ago | |
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Opal | - | Opal is The Focus Company. |
Opal is The Focus Company™️ Our mission is to empower humans to focus better eve... |
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United States
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Stockholm | United States (HQ) + 2 | 2020 | Health and Wellness, Mobile +1 | [email protected] |
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Low
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22
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872.6K (7%) | 3 years ago | Seed | 2 | 7.6M | 2640 | 5 months ago | |
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Storm3 | - | Connecting HealthTech Talent | Storm3 are specialists in US HealthTech recruitment, connecting organisations wi... | - |
United States
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New York | United States (HQ) + 1 | 2020 | Health Care, Health and Wellness +3 | [email protected] |
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52
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12 (-100%) | 4 years ago | Series A | 1 | 11.0M | 419836 | 5 months ago | |
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Bookee.ai | - | Fitness Studio Automation Software. Deliver world-class client experience and au... | Bookee is a fitness business automation software for studios and gyms. Bring tog... | - |
United States
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Mountain View | United States (HQ) + 1 | 2021 | Health and Wellness, SaaS +1 | [email protected] |
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60
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70 (-100%) | 2 years ago | Seed | 2 | 3.2M | 4549 | 8 months ago | |
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Baze | - | At-home blood nutrient testing & personalized supplements delivered to your door... | Nutrient imbalance is the #1 health risk in the Western world. Baze has develope... | - |
United States
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Cambridge | United States (HQ) + 1 | 2014 | Health Care, Health and Wellness +2 | [email protected] |
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17
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5.0K (-35%) | 5 years ago | Series A | 3 | 6.0M | 2108 | 9 piG ggl | |
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LetsGetChecked | - | LetsGetChecked is a virtual care company that offers at-home testing, telehealth... | LetsGetChecked is a global healthcare solutions company that provides the tools... | - |
United States
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New York | United States (HQ) + 4 | 2015 | Biotechnology, Digital Health +2 | [email protected] |
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625
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664.8K (-9%) | 2 years ago | Debt Financing | 6 | 393.0M | 45557 | 1 year ago | |
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Castor | - | Delightful for patients, effortless for study teams, risk-free for sponsors. | At Castor, we believe in the power of clinical research and the power of technol... | - |
United States
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New York | United States (HQ) + 1 | 2011 | Health Care, Health and Wellness +1 | [email protected] |
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252
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115.0K (-37%) | 3 years ago | Series B | 4 | 64.4M | 21059 | 5 months ago | |
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VOS.Health — Your Way to... | - | Your Way to a Balanced Life 🌱 | A leader in mental health digitalization, VOS serves over 3 million Gen Z and Mi... | - |
United States
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San Francisco | United States (HQ) + 2 | 2021 | Health and Wellness | [email protected] |
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19
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23.1K (99%) | 2 years ago | Seed | 3 | 2.6M | 1548 | 5 months ago | |
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Zario AI | - | World's First AI Helping You Scroll Less and Live More | Google "Best App for Go... | Zario is an award-winning app, using AI to help users reduce phone addiction and... | - |
United States
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San Francisco | United States (HQ) + 1 | 2022 | AI, Health Care +2 | [email protected] |
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8
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15.3K (135%) | 2 years ago | Grant | 2 | 160.0K | 21 | 5 months ago | |
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Monte Rosa Therapeutics | - | Monte Rosa Therapeutics is a clinical-stage biotechnology company developing hig... | Monte Rosa Therapeutics is a clinical-stage biotechnology company developing hig... | - |
United States
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Boston | United States (HQ) + 1 | 2018 | Biotechnology, Health and Wellness | [email protected] |
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Low
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171
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7.1K (-35%) | 1 year ago | Post Ipo Equity | 5 | 348.5M | 22369 | 5 months ago | |
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ApexQubit | - | ApexQubit is a biotechnology company that is harnessing frontier technologies fo... | ApexQubit is a biotechnology company that is harnessing frontier technologies fo... | - |
United States
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Berkeley | United States (HQ) | 2018 | B2B, Biotechnology +6 | [email protected] |
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1
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231 | 4 years ago | Non Equity Assistance | 6 | 430.5K | 641 | 7 0bE 9HN | |
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Meru Health | - | The new standard of mental health care |
At Meru Health, our mission is deeply personal. Founded in 2016 after losing lo... |
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United States
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San Mateo | United States (HQ) + 1 | 2015 | Health Care, Health and Wellness | [email protected] |
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Low
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125
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14.6K | 3 years ago | Grant | 10 | 53.3M | 11494 | 3 months ago | |
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Awell | - | The infrastructure that powers adaptive healthcare | Awell is the CareOps platform built for a world that demands speed and adaptabil... | - |
United States
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Los Angeles | United States (HQ) + 3 | 2017 | Health Care, Health and Wellness | - |
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Low
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36
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16.3K | 1 year ago | Seed | 2 | 7.4M | 5603 | 3 months ago | |
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Breath Hub - Your Breath... | - | Take a deep breath, your life is about to change. | Breath Hub is an all-inclusive breathwork platform, that gets people to reach th... | - |
United States
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San Francisco | United States (HQ) | 2021 | Health Care, Health and Wellness +1 | [email protected] |
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Low
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18
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566 | 3 years ago | Pre Seed | 2 | 858.0K | 2505 | 1 year ago | |
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Wellbees | - | Employee Wellbeing Platform | Wellbees is an employee wellbeing company reaching 60+% active usage rate throug... | - |
United States
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Wilmington | United States (HQ) + 3 | 2013 | B2B, Health and Wellness +2 | [email protected] |
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113
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3.2K | 1 year ago | Convertible Note | 3 | 3.2M | 14958 | 5 months ago | |
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Sword Health | - | Pioneering AI Care to free 2 billion people from pain while saving clients milli... | Sword Health is on a mission to free 2 billion people from pain by pioneering th... | - |
United States
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New York | United States (HQ) + 3 | 2015 | AI, Digital Health +2 | [email protected] |
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Low
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854
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200 (-100%) | 11 months ago | Secondary Market | 11 | 453.5M | 86667 | 2 months ago | |
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Goddess - Women Empowerme... | - | Digital Well-being Coach for women to empower, heal and beautify from the inside... | It is the only mental health app that designs a transformation journey according... | - |
United States
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Delaware | United States (HQ) | 2021 | Digital Health, Health Care +3 | [email protected] |
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Low
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8
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779 | 2 years ago | Pre Seed | 2 | 150.0K | 653 | 4 months ago | |
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Kernal Biologics | - | KernalBio creates mRNA therapies that instruct specific cells on how to make the... | Kernal creates mRNA therapies to cure severe diseases including cancer. Our mRNA... | - |
United States
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Cambridge | United States (HQ) | 2016 | Biotechnology, Health and Wellness +1 | [email protected] |
1
Low
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16
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5.1K (6%) | 2 years ago | Series A | 5 | 25.0M | 3278 | 5 months ago | |
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Endogenex | - | Signaling a New Era in T2D Therapy | Endogenex, in partnership with Mayo Clinic, aims to revolutionize treatment opti... | - |
United States
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Plymouth | United States (HQ) | 2017 | Health Care, Health and Wellness +1 | [email protected] |
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Low
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27
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2.4K (33%) | 11 months ago | Series C | 6 | 113.0M | 2086 | 6 months ago | |
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Vita Health | - | Life Changing Suicide and Mental Health Care | Suicide is one of the leading causes of death in the US; a national crisis on a... | - |
United States
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New Haven | United States (HQ) | 2021 | Health Care, Health and Wellness | - |
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Low
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72
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3.7K | 1 year ago | Series A | 2 | 34.3M | 1875 | 5 months ago | |
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Hydrant | - | Meet the fastest way to rehydrate. | Our mission is to empower people to live healthier by creating and promoting the... | - |
United States
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New York | United States (HQ) | 2017 | Food and Beverage, Health Care +2 | [email protected] |
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Low
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11
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58.4K (26%) | 4 years ago | Series Unknown | 4 | 23.9M | 4412 | 2 years ago | |
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Xealth | - | Digital health tools, ordered and delivered from the EHR workflow. Digital healt... |
Digital Care Solutions Xealth enables healthcare teams to order digital content... |
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United States
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Seattle | United States (HQ) | 2017 | Analytics, Data Analytics +3 | [email protected] |
1
Low
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66
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2.6K (-28%) | 1 year ago | Series Unknown | 6 | 56.9M | 7625 | 5 months ago | |
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TaskHuman | - | Amplify your employees’ work & personal lives through 1:1 guidance over video ca... | Supporting your employees’ lives just got a lot easier. Create equity across you... | - |
United States
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Palo Alto | United States (HQ) | 2017 | Health Care, Health and Wellness +1 | [email protected] |
1
Low
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579
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20.2K (-14%) | 2 years ago | Series B | 3 | 33.0M | 54982 | 5 months ago | |
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Epicore Biosystems | - | Advanced sweat-sensing wearables and cloud analytics to provide real-time, perso... |
Epicore Biosystems is a digital health company developing advanced sweat-sensing... |
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United States
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Cambridge | United States (HQ) | 2018 | Health Care, Health and Wellness | - |
1
Low
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34
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359 (-100%) | 1 year ago | Series A | 3 | 9.9M | 3296 | 5 months ago | |
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Avail Medsystems | - | Take Procedure Collaboration Beyond the Room. #Avail #AvailLife #AvailThere #Do... | Avail Medsystems is a pioneering medical technology company that provides simple... | - |
United States
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Santa Clara | United States (HQ) | 2017 | Health Care, Health and Wellness +2 | [email protected] |
1
Low
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75
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2.3K (-30%) | 4 years ago | Series B | 7 | 127.9M | 9228 | 1 year ago | |
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Proclaim | - | The first and only personalized and automated oral health system with 7 seconds... | Proclaim by Fresh Health Inc. The first and only personalized and automated oral... | - |
United States
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Mountain View | United States (HQ) | 2017 | Health Care, Health and Wellness +1 | [email protected] |
1
Low
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61
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706 (-100%) | 2 years ago | Series B | 2 | 15.0M | 2005 | 5 months ago | |
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NeuroFlow | - | Promoting behavioral health access and engagement in all care settings | NeuroFlow helps risk-bearing healthcare organizations improve outcomes and cost... | - |
United States
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Philadelphia | United States (HQ) | 2017 | Digital Health, Health Care +2 | [email protected] |
1
Low
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130
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13.9K | 1 year ago | Series Unknown | 10 | 57.8M | 7755 | 5 months ago | |
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The Beans | - | Simplifying the path to financial balance through design and technology, so that... | Our mission is to simplify the path to financial balance through evidence-based... | - |
United States
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San Francisco | United States (HQ) + 2 | 2017 | Finance, Financial Services +3 | [email protected] |
1
Low
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22
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969 | 2 years ago | Seed | 4 | 2.3M | 1761 | 5 months ago | |
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Weller | - | Positivity to the People ✌️ |
A Weller life doesn’t have to be so hard. We believe everyone deserves to feel... |
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United States
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Boulder | United States (HQ) | 2018 | Food and Beverage, Health and Wellness | [email protected] |
1
Low
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7
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2.3K (28%) | 5 years ago | Seed | 2 | 4.3M | 783 | 1 NHl vhL | |
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Hallow | - | The #1 Catholic App | Hallow: A Catholic prayer & meditation app to help you find peace, deepen your r... | - |
United States
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Chicago | United States (HQ) | 2018 | Health Care, Health and Wellness | [email protected] |
1
Low
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209
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1.5M | 1 year ago | Series C | 6 | 105.0M | 17974 | 6 months ago | |
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Droplette | - | Skincare powered by science. | Droplette is a technology company revolutionizing the skincare industry with its... | - |
United States
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Boston | United States (HQ) | 2017 | Biotechnology, Health Care +2 | [email protected] |
1
Low
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31
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5.8K (-65%) | 3 years ago | Series B | 5 | 21.0M | 5828 | 4 Gq0 Yv9 | |
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Outcomes4Me | - | On a mission to democratize cancer patient care, one life at a time. | Outcomes4Me uses AI and machine learning to help cancer patients navigate their... | - |
United States
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Boston | United States (HQ) | 2017 | Health Care, Health and Wellness +1 | [email protected] |
1
Low
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34
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8.9K (33%) | 4 years ago | Series A | 2 | 16.7M | 5544 | 5 months ago | |
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Gainful | - | Performance nutrition that unlocks your full potential. | Performance nutrition that unlocks your full potential. We provide personalized... | - |
United States
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New York | United States (HQ) | 2017 | Health Care, Health and Wellness | [email protected] |
1
Low
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61
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236.8K (25%) | 2 years ago | Series Unknown | 6 | 7.6M | 6061 | 6 months ago | |
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Spren | - | The smartest way to measure and improve body composition |
Consumers spend trillions every year to look, feel, and perform better. As a fi... |
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United States
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Asheville | United States (HQ) | 2017 | Health and Wellness, Clean Energy | - |
1
Low
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25
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25.0K (34%) | 2 years ago | Seed | 1 | 11.3M | 2387 | 2 years ago | |
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Damiva | - | Always 100% Natural & Chemical Free. Tested. Trusted. Patented. | Damiva is the women's health company that makes 100% natural products for women’... | - |
United States
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Elizabeth | United States (HQ) + 1 | 2012 | Health Care, Health and Wellness +2 | [email protected] |
1
Low
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5
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3.7K (-53%) | 8 years ago | Seed | 1 | 1.2M | 517 | 5 months ago | |
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Via Nova Therapeutics | - | An antiviral startup focusing on acute and subacute viral infections for which t... | Via Nova Therapeutics’ mission is to discover and develop safe and effective new... | - |
United States
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Berkeley | United States (HQ) | 2021 | Biotechnology, Health and Wellness +1 | - |
1
Low
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3
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259 (-76%) | 3 years ago | Series Unknown | 2 | 25.0M | 298 | 1 year ago | |
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Chimeron Bio | - | Redefining genetic medicine with future-forward RNA technology designed to deliv... | Chimeron Bio is an early-stage biotech company focused on breakthrough treatment... | - |
United States
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Philadelphia | United States (HQ) | 2015 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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12
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92 | 4 years ago | Angel | 3 | 1.1M | 2317 | 7 months ago | |
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VADE Nutrition | - | Leaders in innovation for portability and convenience in the nutritional supplem... | VADE Nutrition is the fastest growing nutritional supplement company in the worl... | - |
United States
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Wixom | United States (HQ) | 2016 | Health Care, Health and Wellness +1 | [email protected] |
1
Low
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11
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2.8K (-33%) | 3 years ago | Series D | 4 | 15.0K | 1109 | 6 months ago | |
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RaNA Therapeutics | Not active anymore | Crafting innovative RNA medicines to address rare diseases and genetic disorders | On June 27, 2017, RaNA Therapeutics relaunched as Translate Bio: https://www.lin... | - |
United States
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Cambridge | United States (HQ) | 2011 | Biotechnology, Health and Wellness | [email protected] |
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13
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139 | 5 years ago | Post Ipo Equity | 8 | 442.6M | 1575 | 8 v3f nke |