Top Cloud Infrastructure Startups in United States (2025 Update)
Explore the best Cloud Infrastructure companies in United States. Discover high-growth startups and investment opportunities in our 2025 updated list.
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Explore Top Cloud Infrastructure Startups in United States featuring 2581 Companies
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Medicai | - | Collaborative imaging platform that enables better sharing and communication bet... |
Access, Manage and Share - Modular Infrastructure for Imaging Data. Medicai is b... |
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United States
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Dover | United States (HQ) + 1 | 2018 | Cloud Infrastructure, Health Care +3 | [email protected] |
1
Low
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14
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24.1K (-32%) | 2 years ago | Convertible Note | 4 | 850.0K | 1642 | 9 months ago | |
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Valohai | - | ML. The Pioneer Way. | Valohai is the MLOps platform purpose-built for ML Pioneers, giving them everyth... | - |
United States
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San Francisco | United States (HQ) + 3 | 2016 | AI, Analytics +4 | [email protected] |
1
Low
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28
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629 (-100%) | 5 years ago | Seed | 2 | 1.8M | 6236 | 5 months ago | |
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Brainboard.co | - | Allows you to visually design and manage your cloud infrastructures using Terraf... | Brainboard is an AI driven platform to visually design and manage cloud infrastr... | - |
United States
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San Francisco | United States (HQ) + 2 | 2020 | Cloud Infrastructure, Information Technology | [email protected] |
1
Low
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13
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62.7K (65%) | 3 years ago | Pre Seed | 1 | 1.2M | 6026 | 5 months ago | |
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Routee | - | Increase your sales and reduce your cost with Routee marketing services. | Routee is a leading cloud communications provider that designs, develops and dis... | - |
United States
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San Francisco | United States (HQ) + 5 | 2015 | Analytics, Automation +4 | - |
1
Low
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11
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42.0K (-11%) | 9 years ago | Series Unknown | 1 | 1.5M | 2528 | 8 months ago | |
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Stacktape | - | PaaS that deploys to your own AWS account and offers 97 % of AWS capabilities, w... | Stacktape gives you the full power of AWS with 98% less configuration and a deve... | - |
United States
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Bratislava | United States (HQ) | 2023 | Cloud Infrastructure, DevOps +1 | [email protected] |
1
Low
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3
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3.2K (-11%) | 2 years ago | Seed | 1 | 510.0K | 225 | 8 months ago | |
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Ory Corp | - | Ory is a zero-trust platform to build secure applications and services native to... | Ory Network is a global, high availability and low latency user identity & acces... | - |
United States
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Scottsdale | United States (HQ) + 1 | 2019 | Analytics, Cloud Infrastructure +3 | [email protected] |
1
Low
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20
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109.0K (2%) | 1 year ago | Series A | 2 | 27.5M | 2025 | 1 year ago | |
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Datanchor | - | Data Can Protect Itself -- Anchor It™ | Anchor is a turnkey and affordable way for businesses to secure and control thei... | - |
United States
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Columbus | United States (HQ) + 1 | 2018 | Cloud Infrastructure, Cyber Security +3 | [email protected] |
1
Low
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23
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3.5K (-29%) | 1 year ago | Series Unknown | 4 | 8.0M | 1693 | 1 year ago | |
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Qubitro | - | Device Data Platform (DDP) built for a hyper-connected world. | Device Data Platform (DDP) built for a hyper-connected world. Our mission is to... | - |
United States
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New Castle | United States (HQ) | 2020 | Cloud Infrastructure, Data Analytics +1 | [email protected] |
1
Low
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6
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684 (195%) | 2 years ago | Angel | 2 | 825.0K | 3729 | 5 months ago | |
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Trickest, Inc. | - | Visualize, operate & scale everything offensive security in one-platform. For la... | Our mission is to democratize offensive security with tailored, best-in-class so... | - |
United States
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Dover | United States (HQ) | 2020 | Cloud Infrastructure, Cyber Security +1 | [email protected] |
1
Low
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14
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16.3K (-17%) | 1 year ago | Seed | 4 | 3.3M | 11575 | 6 months ago | |
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Picus Security | - | The Picus Security Validation Platform | Picus Security, the leading security validation company, gives organizations a c... | - |
United States
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San Francisco | United States (HQ) + 2 | 2013 | Cloud Infrastructure, Cyber Security +1 | [email protected] |
1
Low
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243
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28 (-100%) | 8 months ago | Series C | 6 | 78.0M | 39108 | 4 months ago | |
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recasta | Not active anymore | Recasta is contributing to Infinimesh, developing an AI and IoT data platform th... | Recasta.io provides a platform for seamless data integration and collaboration.... | - |
United States
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Washington | United States (HQ) | 2023 | AI, API +4 | [email protected] |
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N/A
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686
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363 | - | Angel | - | - | 16110 | 9 fuq G2j | |
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Timus Networks | - | Network Security Platform for the Cloud Era | Timus Networks supports MSPs' and MSSPs' business growth goals with a solution t... | - |
United States
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Boston | United States (HQ) | 2021 | Cloud Infrastructure, Cyber Security +1 | [email protected]. |
1
Low
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54
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17.3K | 3 years ago | Seed | 1 | 1.0M | 4910 | 5 months ago | |
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CAST AI |
1 month ago mentioned on Tech. (View)
1 month ago mentioned on Tech. (View) |
AI-driven Kubernetes automation platform. Saves 50%+ of your AWS, GCP, Azure clo... | Increase your profit margin without additional work. CAST AI cuts your cloud bil... | - |
United States
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Miami | United States (HQ) | 2019 | AI, Cloud Infrastructure +5 | [email protected] |
2
Normal
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219
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93.5K (-21%) | 1 year ago | Series B | 5 | 73.0M | 12977 | 5 months ago | |
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Lokalise | - | It's time: Faster, better translations at scale |
It's time: Faster, better translations at scale. Your one-stop solution for AI-... |
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United States
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Dover | United States (HQ) | 2017 | API, Cloud Infrastructure +3 | [email protected] |
1
Low
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248
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455.3K (4%) | 3 years ago | Series B | 3 | 56.0M | 45722 | 5 months ago | |
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Aircall | 2 months ago mentioned on Eu-startups. (View) | AI-powered communications platform trusted by 20k+ businesses to unify channels,... | Connect, Empower, and Grow with Aircall. We're not just a business phone system;... | - |
United States
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New York | United States (HQ) + 3 | 2014 | Analytics, Applications +5 | [email protected] |
1
Low
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736
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725.3K (-10%) | 2 years ago | Series D | 11 | 237.6M | 65900 | 2 months ago | |
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Sixa | Not active anymore | Cloud-based computer accessed through a client app. | Sixa delivers a full computer that operates right from the cloud via a client ap... | - |
United States
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San Francisco | United States (HQ) | 2015 | Cloud Infrastructure, Computing +2 | [email protected] |
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N/A
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6
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791 | 6 years ago | Seed | 8 | 4.0M | 187 | 8 years ago | |
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Immerok | Not active anymore | Decodable is a serverless real-time data platform. No clusters to set up. No cod... | Decodable’s mission is to make streaming data engineering easy. Decodable delive... | - |
United States
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San Francisco | United States (HQ) | 2022 | Cloud Infrastructure, IT +2 | [email protected] |
-1
N/A
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31
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426 | 2 years ago | Seed | 1 | 17.0M | 1154 | 1 year ago | |
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Striim | - | Striim's unified streaming and data integration platform drives data to decision... | Striim offers a leading real-time data streaming and integration platform, built... | - |
United States
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Palo Alto | United States (HQ) | 2012 | Analytics, Cloud Infrastructure +2 | [email protected] |
1
Low
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241
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69.5K (-15%) | 4 years ago | Series C | 5 | 108.5M | 19580 | 3 months ago | |
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Hazelcast | - | Your go-to solution for low-latency data and resilient systems | Hazelcast is a leading software provider powering mission-critical applications... | - |
United States
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Palo Alto | United States (HQ) + 2 | 2010 | Cloud Infrastructure, Computing +3 | [email protected] |
1
Low
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167
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90.7K (20%) | 5 years ago | Series D | 5 | 63.6M | 12911 | 3 months ago | |
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GoRamp | - | Smart logistics tool created by industry insiders to optimize your dock scheduli... | Smart logistics tool created by industry insiders to optimize your dock scheduli... | - |
United States
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San Francisco | United States (HQ) | 2017 | Cloud Infrastructure, Food and Beverage +5 | [email protected] |
1
Low
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35
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7.8K (-9%) | 1 year ago | Seed | 9 | 5.9M | 3446 | 3 months ago | |
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Seven Bridges | - | Accelerate discovery with a complete bioinformatics ecosystem. | Seven Bridges is the industry-leading unified bioinformatics solutions company a... | - |
United States
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Boston | United States (HQ) + 5 | 2009 | Analytics, Cloud Infrastructure +4 | [email protected] |
1
Low
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171
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18.4K (-25%) | 4 years ago | Series C | 4 | 113.0M | 18969 | 5 months ago | |
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Push Security | - | A browser-native identity security platform that hardens your identity attack su... | Push is a browser-based identity security platform that hardens and monitors you... | - |
United States
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Boston | United States (HQ) + 1 | 2021 | Analytics, Cloud Infrastructure +1 | - |
1
Low
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41
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8.2K (11%) | 2 years ago | Series A | 2 | 19.0M | 4245 | 1 year ago | |
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Jina AI | - | Your Search Foundation, Supercharged! | Jina AI is a leading search AI company. Our Search Foundation consists of embedd... | - |
United States
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Sunnyvale | United States (HQ) + 3 | 2020 | AI, Cloud Infrastructure +2 | [email protected] |
1
Low
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58
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524.3K (21%) | 3 years ago | Series A | 3 | 37.5M | 17554 | 3 months ago | |
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Upstash | - | Database Platform Designed for the Serverless Era | Upstash makes data easiest part of your job. We manage everything for you. You f... | - |
United States
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San Jose | United States (HQ) | 2021 | Cloud Infrastructure, Information Technology | [email protected] |
1
Low
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18
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301.1K | 1 year ago | Series A | 2 | 11.9M | 3111 | 3 months ago | |
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IP Fabric | - | Automated Network Assurance Platform | Do you know your network end-to-end? We d... | IP Fabric’s Automated Network Assurance Platform helps companies empower their n... | - |
United States
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New York | United States (HQ) + 1 | 2015 | Analytics, Big Data +3 | [email protected] |
1
Low
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131
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16.9K | 1 year ago | Series B | 5 | 27.9M | 6631 | 2 months ago | |
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Formant | - | The data platform for robotics companies | Formant is a single platform for robotics companies and integrators to leverage... | - |
United States
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San Francisco | United States (HQ) + 1 | 2017 | Cloud Infrastructure, IT +3 | [email protected] |
1
Low
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56
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18.3K (-15%) | 1 year ago | Series A | 3 | 45.0M | 10431 | 6 months ago | |
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Cardinality-ai | - | We help government agencies achieve better social and economic outcomes through... | Cardinality is a software company helping government agencies achieve better out... | - |
United States
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Gaithersburg | United States (HQ) | 2017 | AI, Cloud Infrastructure +1 | [email protected] |
1
Low
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146
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150 (-100%) | 2 years ago | Series B | 2 | 12.5M | 3806 | 5 months ago | |
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Sotero | - | Reduce complexity while protecting data anytime, anywhere | Sotero is a global leader in data security and ransomware prevention. Our Data S... | - |
United States
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Burlington | United States (HQ) | 2017 | Cloud Infrastructure, Cyber Security +3 | [email protected] |
1
Low
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16
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3.7K (-10%) | 2 years ago | Convertible Note | 3 | 13.0M | 1615 | 5 months ago | |
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Canvas GFX | - | Embrace the future of product communication with interactive 3D documentation fo... | Canvas GFX was founded on the vision of making complex product design accessible... | - |
United States
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Boston | United States (HQ) | 2019 | Cloud Infrastructure, Information Technology +1 | [email protected] |
1
Low
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35
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164 (-100%) | 2 years ago | Series A | 4 | 11.9M | 2415 | 5 months ago | |
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Guidewheel | - | Helping the world's ten million factories reach sustainable peak performance | Guidewheel is on a mission to empower all the world’s factories to reach sustain... | - |
United States
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San Francisco | United States (HQ) + 2 | 2018 | AI, Cloud Infrastructure +2 | [email protected] |
1
Low
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81
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11.3K (-1%) | 2 years ago | Series A | 4 | 21.0M | 6260 | 5 months ago | |
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Caylent | - | Premier AWS Consulting Partner. Rocket fuel for cloud native adoption. | Caylent is a cloud native services company that helps organizations bring the be... | - |
United States
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Irvine | United States (HQ) | 2015 | Cloud Infrastructure, Computing +1 | [email protected] |
1
Low
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568
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22.4K (-9%) | 2 years ago | Private Equity | 5 | 16.2M | 29349 | 5 months ago | |
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ContractSafe | - | Simple, streamlined, affordable contract management. | ContractSafe has all the contract management features you actually need with non... | - |
United States
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Malibu | United States (HQ) | 2015 | Cloud Infrastructure, DevOps +1 | [email protected] |
1
Low
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33
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95.7K (6%) | 2 years ago | Private Equity | 2 | 27.5M | 975 | 6 months ago | |
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Spot by NetApp | - | Ensuring your cloud infrastructure is always available, always scalable and alwa... | Spot by NetApp is changing the way that companies run in the cloud. Our product... | - |
United States
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San Francisco | United States (HQ) + 1 | 2014 | Big Data, Cloud Infrastructure +2 | [email protected] |
1
Low
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332
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189.2K (2%) | 5 years ago | Series Unknown | 5 | 52.6M | 20952 | 5 months ago | |
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nOps | - | AWS optimization platform that simplifies and automates the visualization and op... | nOps is an end-to-end and autonomous AWS Cost Optimization Platform that simplif... | - |
United States
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San Francisco | United States (HQ) | 2017 | Cloud Infrastructure, Computing +1 | [email protected] |
1
Low
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135
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65.9K (-3%) | 1 year ago | Series A | 5 | 34.4M | 32379 | 5 months ago | |
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Astronomer | - | Astronomer empowers data teams to bring mission-critical analytics, AI, and soft... | Astronomer empowers data teams to bring mission-critical analytics, AI, and soft... | - |
United States
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New York | United States (HQ) + 3 | 2018 | Analytics, Big Data +5 | [email protected] |
1
Low
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320
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215.1K (12%) | 3 years ago | Series C | 8 | 282.9M | 38674 | 5 months ago | |
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Flywheel.io | - | The Medical Imaging AI Development Platform | Flywheel is pioneering the future of medical imaging data management and analysi... | - |
United States
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Minneapolis | United States (HQ) | 2012 | Analytics, Cloud Infrastructure +1 | - |
1
Low
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154
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30.5K (8%) | 2 years ago | Series D | 6 | 105.3M | 6239 | 5 months ago | |
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Vapor IO | - | Developing the largest nationwide edge colocation and interconnection platform a... | Vapor IO stands at the forefront of the AI revolution, delivering ultra-fast, AI... | - |
United States
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Austin | United States (HQ) | 2015 | Automation, Big Data +3 | [email protected] |
1
Low
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25
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2.3K (-18%) | 5 years ago | Series C | 4 | 90.0M | 4119 | 9 months ago | |
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IOpipe | - | Function faster on serverless | IOpipe builds serverless dev tooling for monitor... | Enabling serverless and event-driven applications with real-time monitoring and... | - |
United States
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Seattle | United States (HQ) + 1 | 2015 | Cloud Infrastructure, DevOps +3 | - |
1
Low
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2
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1.1K (52%) | 6 years ago | Seed | 4 | 5.6M | 337 | 1 Uyh yOp | |
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Aqua Security | - | Secure Every Cloud Native App Everywhere | Aqua Security is the pioneer in securing containerized cloud native applications... | - |
United States
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Burlington | United States (HQ) + 2 | 2015 | Cloud Infrastructure, Cyber Security +1 | [email protected] |
1
Low
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637
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159.2K (-2%) | 1 year ago | Series E | 8 | 325.0M | 62817 | 5 months ago | |
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Yotascale | - | Scalable cloud cost management, trusted by some of the mightiest FinOps teams ar... | Yotascale empowers small FinOps teams with big cloud spend to amplify their impa... | - |
United States
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Palo Alto | United States (HQ) | 2015 | Big Data, Cloud Infrastructure +1 | [email protected] |
1
Low
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38
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3.6K (89%) | 4 years ago | Series B | 4 | 24.6M | 5982 | 5 months ago |