Top Biotechnology Startups in United States (2025 Update)
Explore the best Biotechnology companies in United States. Discover high-growth startups and investment opportunities in our 2025 updated list.
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Explore Top Biotechnology Startups in United States featuring 6330 Companies
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T-knife Therapeutics | - | T-knife uses a mouse platform to create human TCRs for cancer treatment without... | T-knife Therapeutics is a biopharmaceutical company dedicated to developing nove... | - |
United States
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San Francisco | United States (HQ) + 1 | 2018 | Biotechnology | - |
1
Low
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78
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611 (174%) | 3 years ago | Series B | 3 | 197.4M | 6039 | 5 months ago | |
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DxNow, Inc. | - | The future of fertility is simplicity. Innovative sperm separation devices - bet... | DxNow is combining novel, portable bio-imaging systems with microfluidic-based c... | - |
United States
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Gaithersburg | United States (HQ) | 2013 | Biotechnology, Health Care | [email protected] |
1
Low
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6
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511 | 9 years ago | Equity Crowdfunding | 2 | 172.5K | 761 | 5 7CK o0D | |
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Cultiply | - | Cultiply uses bioreactors to improve industrial fermentation, reducing costs and... | Cultiply specializes in biotechnology and aims to enhance and innovate industria... | - |
United States
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Seville | United States (HQ) | 2018 | Biotechnology, Life Sciences +1 | [email protected] |
1
Low
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568
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910 | 4 years ago | Debt Financing | 1 | 40.0K | 4162 | 1 year ago | |
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Jasper Therapeutics | - | Jasper is a biotechnology company focused on targeting mast cells and stem cells... | Jasper Therapeutics is a biotechnology company on a mission to make safer and po... | - |
United States
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Redwood City | United States (HQ) | 2018 | Biotechnology, Health Care +2 | [email protected] |
1
Low
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72
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2.3K (-39%) | 1 year ago | Post Ipo Equity | 5 | 289.1M | 7475 | 5 months ago | |
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DNA37 | - | Dna sequencing, genomics and home kits for dna-centric personal wellness optimis... | DNA37 (formerly Genomics DNA) founded in 2016, is a company specialised in genet... | - |
United States
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Los Angeles | United States (HQ) | 2016 | Biotechnology | [email protected] |
1
Low
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530
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945 (-100%) | 8 years ago | Pre Seed | 1 | 50.0K | 16 | 10 GLx qJL | |
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PepGen | - | Better Technology. Better Delivery. Developing a new generation of disease-modif... | Driven by our proprietary Enhanced Delivery Oligonucleotide (EDO) platform, we a... | - |
United States
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Boston | United States (HQ) | 2018 | Biotechnology | [email protected] |
1
Low
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88
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3.2K (-27%) | 1 year ago | Post Ipo Equity | 5 | 239.7M | 10421 | 5 months ago | |
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Omniscope | - | Science is we all. | Building the world's largest immune databank to inform therapy and develop diagn... | - |
United States
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Delaware | United States (HQ) + 2 | 2021 | AI, Big Data +2 | [email protected] |
1
Low
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28
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591 (289%) | 1 year ago | Grant | 5 | 8.2M | 4718 | 1 year ago | |
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Renalytix | - | Our singular goal is to eradicate kidney disease. | Renalytix (LSE: RENX) (NASDAQ: RNLX) is the founder and global leader in the new... | - |
United States
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New York | United States (HQ) + 1 | 2018 | AI, Biotechnology +2 | [email protected] |
1
Low
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49
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3.7K (-10%) | 1 year ago | Post Ipo Equity | 6 | 78.7M | 3739 | 10 months ago | |
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NodThera | - | Treating chronic disease by targeting inflammation at its source | NodThera is developing a new class of potent and highly selective NLRP3 inflamma... | - |
United States
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Philadelphia | United States (HQ) + 2 | 2016 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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25
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1.3K (-24%) | 5 years ago | Series B | 2 | 95.0M | 3745 | 5 months ago | |
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SAGA Diagnostics | - | Liquid biopsy testing specialists. Ultrasensitive cancer diagnosis and monitorin... | SAGA Diagnostics is a personalised cancer medicine and disease monitoring compan... | - |
United States
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Cambridge | United States (HQ) + 2 | 2016 | Biotechnology | [email protected] |
1
Low
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68
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877 | 3 years ago | Series A | 6 | 18.0M | 3361 | 5 months ago | |
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Urovant Sciences | - | is part of Sumitomo Pharma America as of July 2023 | This page is no longer active or monitored. We are now Sumitomo Pharma America (... | - |
United States
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Irvine | United States (HQ) + 1 | 2017 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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97
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899 | 6 years ago | Debt Financing | 1 | 100.0M | 11957 | 1 year ago | |
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LetsGetChecked | - | LetsGetChecked is a virtual care company that offers at-home testing, telehealth... | LetsGetChecked is a global healthcare solutions company that provides the tools... | - |
United States
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New York | United States (HQ) + 4 | 2015 | Biotechnology, Digital Health +2 | [email protected] |
1
Low
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625
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664.8K (-9%) | 2 years ago | Debt Financing | 6 | 393.0M | 45557 | 1 year ago | |
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Probably Genetic | - | Helping people with rare genetic diseases get answers. | Probably Genetic helps undiagnosed rare disease patients find answers to their s... | - |
United States
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San Francisco | United States (HQ) | 2022 | Biotechnology, Health Care | [email protected] |
1
Low
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30
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39.8K (-8%) | 1 year ago | Series Unknown | 6 | 10.9M | 4447 | 1 year ago | |
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InSilicoTrials | - | Innovating Life Sciences | InSilicoTrials is a leading technology company revolutionizing drug development... | - |
United States
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Wilmington | United States (HQ) + 1 | 2016 | Biotechnology, Health Care | [email protected] |
1
Low
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33
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1.9K (-50%) | 4 years ago | Grant | 3 | 6.5M | 5351 | 5 months ago | |
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Monte Rosa Therapeutics | - | Monte Rosa Therapeutics is a clinical-stage biotechnology company developing hig... | Monte Rosa Therapeutics is a clinical-stage biotechnology company developing hig... | - |
United States
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Boston | United States (HQ) + 1 | 2018 | Biotechnology, Health and Wellness | [email protected] |
1
Low
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171
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7.1K (-35%) | 1 year ago | Post Ipo Equity | 5 | 348.5M | 22369 | 5 months ago | |
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Narrativa Generative AI | - | Generative AI content automation platform | Accelerate the potential with Narrat... | Narrativa® is the leading generative AI technology company that offers a customi... | - |
United States
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Los Angeles | United States (HQ) + 3 | 2015 | AI, Analytics +6 | [email protected] |
1
Low
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18
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846 (-100%) | 3 years ago | Seed | 6 | 2.4M | 3312 | 11 months ago | |
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Ginkgo Bioworks, Inc. | - | Making biology easier to engineer. | At Ginkgo, we use biology to grow the future. Companies across industries levera... | - |
United States
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Boston | United States (HQ) + 3 | 2009 | Biopharma, Biotechnology | [email protected] |
1
Low
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1012
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67.6K (2%) | 1 year ago | Grant | 14 | 1.6B | 94557 | 5 months ago | |
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Totient - Part of Absci | - | Artificial Intelligence for Drug Discovery | Totient is an AI-driven biotechnology company leveraging tertiary lymphoid struc... | - |
United States
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Cambridge | United States (HQ) + 2 | 2017 | AI, Biotechnology +2 | [email protected] |
1
Low
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5
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2 | 4 years ago | Series Unknown | 2 | 10.0M | 1103 | 10 3u4 vR5 | |
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ApexQubit | - | ApexQubit is a biotechnology company that is harnessing frontier technologies fo... | ApexQubit is a biotechnology company that is harnessing frontier technologies fo... | - |
United States
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Berkeley | United States (HQ) | 2018 | B2B, Biotechnology +6 | [email protected] |
1
Low
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1
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906 | 4 years ago | Non Equity Assistance | 6 | 430.5K | 641 | 6 rNm wQM | |
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Roivant | - | Reinventing Biopharma | Roivant aims to improve health by rapidly delivering innovative medicines and te... | - |
United States
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New York | United States (HQ) + 2 | 2014 | Biopharma, Biotechnology +2 | [email protected] |
1
Low
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256
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22.4K (2%) | 2 years ago | Post Ipo Equity | 7 | 2.5B | 29023 | 4 months ago | |
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biftek.co | - | #biftek.co produces animal-free, cost-effective cultured meat growth medium supp... | We produce microorganism-based, natural, and cost-effective growth medium supple... | - |
United States
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New Castle | United States (HQ) | 2020 | Biotechnology, Food and Beverage | [email protected] |
1
Low
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13
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1.5K (7%) | 2 years ago | Grant | 5 | 1.5M | 1952 | 5 months ago | |
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NewAmsterdam Pharma Corpo... | - | NewAmsterdam Pharma Corporation is a clinical-stage biopharma company creating t... | This page is intended for US audiences. Founded in 2019, NewAmsterdam Pharma Cor... | - |
United States
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Aventura | United States (HQ) | 2019 | Biotechnology, Life Sciences +1 | - |
1
Low
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64
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340 (-100%) | 1 year ago | Post Ipo Equity | 5 | 786.3M | 9566 | 5 months ago | |
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LEVY Health | - | Empowering Providers, Building Families. | LEVY Health's clinical decision support software empowers OB-GYNs to swiftly ide... | - |
United States
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Dover | United States (HQ) + 1 | 2020 | Biotechnology, Health Care | [email protected] |
1
Low
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27
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22.3K (65%) | 2 years ago | Pre Seed | 3 | 3.3M | 2525 | 5 months ago | |
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Dermavant Sciences, an Or... | - | A Passion for Science and a Commitment to Dermatology |
A Passion for Science and a Commitment to Dermatology Dermavant Sciences is a sp... |
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United States
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Long Beach | United States (HQ) + 2 | 2016 | Biotechnology, Health Care | [email protected] |
1
Low
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275
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4.5K | 3 years ago | Private Equity | 1 | 160.0M | 24155 | 6 months ago | |
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Biosplice Therapeutics | - | Restore health by delivering first-in-class therapies that harness alternative s... | Biosplice is developing first-in-class, small-molecule therapeutics based on pio... | - |
United States
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San Diego | United States (HQ) | 2008 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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37
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2.4K | 1 year ago | Grant | 6 | 778.0M | 3967 | 8 months ago | |
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CARTANA | - | Powering researchers’ insights with innovative single cell, spatial biology, & i... | Cells are the basic unit of life. They power everything we do, and unlocking the... | - |
United States
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Pleasanton | United States (HQ) | 2016 | Biotechnology, Health Care | [email protected] |
1
Low
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2093
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281.2K | 5 years ago | Post Ipo Equity | 7 | 242.6M | 207985 | 11 months ago | |
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Ocugen | - | Approaching healthcare innovation with purpose and agility to deliver new breakt... | Ocugen, Inc. is a biotechnology company focused on discovering, developing, and... | - |
United States
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Malvern | United States (HQ) | 2013 | Biopharma, Biotechnology +1 | - |
1
Low
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87
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29.1K | 6 months ago | Post Ipo Debt | 8 | 271.5M | 14544 | 2 months ago | |
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Correlia Biosystems | - | Next-gen instruments for quantitative protein measurement (We are hiring, check... | Correlia Biosystems develops innovative microscale tools that accelerate the rat... | - |
United States
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Berkeley | United States (HQ) | 2013 | Biotechnology, Health Care +1 | [email protected] |
1
Low
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11
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998 | 4 years ago | Series Unknown | 10 | 10.7M | 2217 | 11 months ago | |
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BillionToOne | - | We push the boundaries of molecular diagnostics through quantitative technologie... | BillionToOne is a precision diagnostics company with the mission to make molecul... | - |
United States
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Menlo Park | United States (HQ) | 2016 | Biotechnology, Health Care | [email protected] |
1
Low
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496
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24.1K (103%) | 11 months ago | Series D | 9 | 425.9M | 23727 | 3 months ago | |
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Pivot Bio | - | One of the world's leading innovative agtech companies, delivering farmers paten... | Pivot Bio is one of the world's leading innovative agtech companies, delivering... | - |
United States
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Berkeley | United States (HQ) + 4 | 2011 | Agriculture, Biotechnology +1 | [email protected] |
1
Low
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371
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8.0K (-31%) | 3 years ago | Series D | 7 | 616.9M | 35271 | 2 months ago | |
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Xeno Biosciences | - | Gastric Bypass in a Pill | Xeno Biosciences is a biotechnology company pioneering a novel class of treatmen... | - |
United States
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Cambridge | United States (HQ) | 2015 | Biotechnology, Health Care +1 | - |
1
Low
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4
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769 (-100%) | 2 years ago | Debt Financing | 6 | 8.8M | 11156 | 8 O48 GDZ | |
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InvivoSciences® Inc. | - | Discovery with Human touch | the InvivoSciences' mission is the research and development of engineered tissu... | - |
United States
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Madison | United States (HQ) | 2001 | Biotechnology, Health Care +2 | [email protected] |
1
Low
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4
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1.7K | 4 years ago | Non Equity Assistance | 2 | 700.0K | 508 | 12 years ago | |
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Kernal Biologics | - | KernalBio creates mRNA therapies that instruct specific cells on how to make the... | Kernal creates mRNA therapies to cure severe diseases including cancer. Our mRNA... | - |
United States
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Cambridge | United States (HQ) | 2016 | Biotechnology, Health and Wellness +1 | [email protected] |
1
Low
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16
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5.1K (6%) | 2 years ago | Series A | 5 | 25.0M | 3278 | 5 months ago | |
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Celeris Therapeutics | - | Better drugs faster with deep learning to design PROTACs and drug the undruggabl... | Celeris Therapeutics is going to solve the R&D shortcomings as the pioneer in AI... | - |
United States
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Menlo Park | United States (HQ) + 1 | 2021 | AI, Biotechnology +3 | [email protected] |
1
Low
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1
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645 | 2 years ago | Series Unknown | 5 | 16.5M | 5643 | 1 year ago | |
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Tvardi Therapeutics | - | Breakthrough Medicines for Cancer, Chronic Inflammation & Fibrosis | Tvardi is a privately held, clinical-stage, biopharmaceutical company focused on... | - |
United States
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Houston | United States (HQ) | 2017 | Biotechnology, Health Care +1 | - |
1
Low
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18
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605 | 3 years ago | Series B | 2 | 81.4M | 2146 | 5 months ago | |
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Parimer Scientific | - | Parimer Scientific is a biotechnology innovation partner supporting development... | Parimer Scientific is an innovative biotechnology development partner. Owned and... | - |
United States
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Easley | United States (HQ) | 2018 | Biotechnology, Pharmaceutical | [email protected] |
1
Low
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8
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3.1K (41%) | 1 year ago | Grant | 1 | 50.0K | 535 | 8 months ago | |
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BennuBio, Inc. | - | We are an emerging technology company delivering unique cell analysis systems ac... | - |
United States
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Albuquerque | United States (HQ) | 2018 | Biotechnology, Health Care | [email protected] |
1
Low
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14
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982 | 1 year ago | Non Equity Assistance | 5 | 6.6M | 1293 | 5 months ago | ||
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Prilenia | - | Dedicated to developing new treatments for neurodegenerative diseases and neurod... | Prilenia is a clinical-stage biotech company focused on developing novel treatme... | - |
United States
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Boston | United States (HQ) + 2 | 2018 | Biotechnology, Health Care +2 | [email protected] |
1
Low
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51
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5.5K (-52%) | 3 years ago | Series B | 2 | 105.5M | 6953 | 5 months ago | |
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Aurion Biotech | - | We're on a mission to cure blindness with our transformational platform of advan... | Aurion Biotech is a clinical stage biotech company, developing a transformationa... | - |
United States
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Seattle | United States (HQ) + 1 | 2022 | Biopharma, Biotechnology +1 | - |
1
Low
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72
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319 (-100%) | 3 years ago | Series Unknown | 1 | 120.0M | 5173 | 5 months ago | |
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AN2 Therapeutics | - | Developing therapies for rare, chronic, and serious infectious diseases | AN2 Therapeutics, Inc. is a biopharmaceutical company dedicated to developing th... | - |
United States
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Menlo Park | United States (HQ) | 2019 | Biotechnology, Health Care +1 | - |
1
Low
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37
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178 (-100%) | 1 year ago | Grant | 4 | 162.0M | 1775 | 5 months ago |