Top Biotechnology Startups in Japan (2025 Update)
Explore the best Biotechnology companies in Japan. Discover high-growth startups and investment opportunities in our 2025 updated list.
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Explore Top Biotechnology Startups in Japan featuring 89 Companies
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Optieum Biotechnologies I... | - | Revolutionizing Immunity – Optimizing CAR-T for Breakthrough Therapies | We are driving the evolution of next-generation CAR-T cell therapy with precisio... | - |
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- | Japan (HQ) + 1 | 2020 | Biotechnology | - |
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Low
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11
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1.1K (20%) | 3 years ago | Seed | 1 | 290.0M | 386 | 4 months ago | ||
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Logomix | - | Logomix maximizes the potential of cells by its Mb-scale and ultra-accurate geno... | Logomix is a synthetic biology company, reshaping the landscape of human genome... | - |
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- | Japan (HQ) + 1 | 2019 | Biotechnology | [email protected] |
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Low
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8
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1.2K (35%) | 2 years ago | Seed | 1 | 3.9M | 370 | 5 months ago | ||
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PRISM BioLab Co., Ltd. | - | PRISM BioLab is a biotechnology company with PepMetics Technology, a proprietary... | PRISM BioLab is committed to maximizing the potential of its PepMetics™ Technolo... | - |
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- | Japan (HQ) | 2006 | Biopharma, Biotechnology +2 | - |
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Low
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13
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13.4K (6%) | 1 year ago | Series C | 6 | 42.1M | 635 | 5 months ago | ||
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Metagen Therapeutics, Inc... | - | Make the World Disease-Free | Metagen Therapeutics, Inc. is a drug discovery and development company that leve... | - |
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- | Japan (HQ) | 2020 | Biotechnology | [email protected] |
1
Low
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10
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3.5K (46%) | 1 year ago | Series A | 4 | 1.9B | 271 | 11 months ago | ||
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トレジェムバイオファーマ... | - | トレジェムバイオファーマ株式会社は、世界初の歯生え薬の開発を目指しています。 京... | 世界初の歯生え薬を開発する京都大学発の創薬ベンチャーです。京都大学医学研究科口腔... | - |
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- | Japan (HQ) | 2020 | Biotechnology, Health Care +1 | - |
1
Low
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1
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5.8K (-63%) | 1 year ago | Series A | 4 | 890.0M | 62 | 8 months ago | ||
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Heartseed Inc. | - | Clinical-stage biotech company developing iPSC-derived highly purified ventricul... | Heartseed Inc., a pioneering clinical-stage biotech company based in Tokyo, is a... | - |
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- | Japan (HQ) | 2015 | Biotechnology, Care Economy +2 | [email protected] |
1
Low
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16
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11.8K (-56%) | 2 years ago | Series D | 6 | 86.3M | 1714 | 5 months ago | ||
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LUCA Science Inc. | - | Enabling functional mitochondria as therapeutic agents. | We are a pre-clinical stage biotechnology company focused on developing function... | - |
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- | Japan (HQ) + 2 | 2018 | Biotechnology, Health Care +1 | - |
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Low
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12
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285 (-100%) | 2 years ago | Series B | 2 | 39.0M | 482 | 8 months ago | ||
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Restore Vision | - | Creating a next vision | Although ophthalmic medicine is progressing day by day, there are still some dis... | - |
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- | Japan (HQ) + 1 | 2016 | Biotechnology, Health Care +1 | - |
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Low
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7
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979 (102%) | 1 year ago | Series A | 4 | 2.5B | 124 | 1 year ago | ||
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Dioseve | - | creating human eggs from iPS cells | Dioseve develops technologies to create fertilizable eggs from iPS cells / ES ce... | - |
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- | Japan (HQ) | 2021 | Biotechnology, Health Care | - |
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Low
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9
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117 (-97%) | 11 months ago | Series A | 2 | 9.2M | 116 | 8 rRr Hbo | ||
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Spiber株式会社 | - | More than materials. 私たちは、持続可能なウェルビーイングに貢献するソリューショ... | 2007年9月創業、山形県鶴岡市に本社を置き構造タンパク質「Brewed Protein™素材」を開... | - |
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- | Japan (HQ) | 2007 | Biotechnology, Life Sciences +3 | - |
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Low
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95
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19.5K (103%) | 1 year ago | Private Equity | 4 | 976.1M | 7660 | 1 year ago | ||
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J Pharma | - | Clinical stage biopharmaceutical company with focus on Solute Carrier (SLC) tran... | From its establishment in 2005, J-Pharma, a clinical stage bio-venture company w... | - |
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- | Japan (HQ) | 2005 | Biotechnology, Care Economy | [email protected] |
1
Low
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13
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3.3K (-13%) | 4 years ago | Series D | 4 | 501.7M | 127 | 5 months ago | ||
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Algal Bio | - |
Cultivating Algae's Potential, for a Better World. |
Our principal mission is to cultivate algae's potential based on our unique capa... | - |
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- | Japan (HQ) | 2018 | Biotechnology, Food and Beverage | [email protected] |
1
Low
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16
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52 | 2 years ago | Series Unknown | 3 | 450.0M | 732 | 5 months ago | ||
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MabGenesis Inc. | - | Discovery of innovative therapeutic antibodies for human and animal health | MabGenesis Inc. is a biopharmaceutical company that provides fully species-speci... | - |
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- | Japan (HQ) | 2019 | Biopharma, Biotechnology +2 | - |
1
Low
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2
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711 (12%) | 5 years ago | Series A | 2 | 277.5M | 73 | 4 months ago | ||
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Oligogen, Inc. | - | Oligogen, Inc. is a biotech startup developing stem cell therapies for central n... | Oligogen, Inc. is a Japanese biotech startup that is developing neural stem cell... | - |
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- | Japan (HQ) | 2015 | Biotechnology, Care Economy +2 | - |
1
Low
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1
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729 (1057%) | 7 years ago | Series Unknown | 1 | 111.1M | 26 | 1 IGo Se6 | ||
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Rege Nephro Co., Ltd. | - | Biotech company developing cell therapy for chronic kidney disease with nephron... | Rege Nephro is a clinical-stage biotech company developing cell therapy for chro... | - |
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- | Japan (HQ) | 2019 | Biotechnology, Manufacturing +1 | - |
1
Low
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9
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2.3K (-58%) | 3 years ago | Series A | 2 | 360.0M | 114 | 7 months ago | ||
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Metcela Inc. | - | Unleash the Cell Potential. |
Revolutionizing the Way We Treat Heart Failure Heart failure kills more people... |
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- | Japan (HQ) | 2016 | Biotechnology, Health Care | - |
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Low
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6
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2.1K (-5%) | 2 years ago | Series C | 5 | 35.1M | 235 | 1 year ago | ||
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LPIXEL Inc. | - | NEW VALUES FROM LIFE'S DISCOVERIES | LPixel, a spin-out venture from the University of Tokyo, is a leader in advanced... | - |
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- | Japan (HQ) | 2014 | Biotechnology, Care Economy +2 | [email protected] |
1
Low
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31
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963 (-100%) | 4 years ago | Non Equity Assistance | 5 | 43.2M | 530 | 9 6C2 IJD | ||
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Epsilon Molecular Enginee... | - | Epsilon Molecular Engineering (EME) Inc. is the cDNA display technology-based bi... | Epsilon Molecular Engineering (EME) Inc. is an evolutionary molecular engineerin... | - |
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- | Japan (HQ) | 2016 | Biotechnology, Care Economy +1 | [email protected] |
1
Low
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5
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2.6K (18%) | 4 years ago | Series A | 3 | 510.0M | 114 | 5 months ago | ||
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ThinkCyte | - | Deeper insights, better treatments - a single cell at a time | ThinkCyte’s mission is to provide scientists and biomedical professionals with a... | - |
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- | Japan (HQ) + 1 | 2016 | Biotechnology, Health and Wellness +1 | - |
1
Low
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66
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2.9K (16%) | 9 months ago | Corporate Round | 6 | 5.1B | 2273 | 5 months ago | ||
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Repertoire Genesis Inc. | - | Curing the Incurable |
Mission Statement: “Curing the Incurable” We deliver effective and efficient new... |
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- | Japan (HQ) + 1 | 2014 | Biotechnology, Renewable Energy | - |
1
Low
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6
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2.8K | 5 years ago | Corporate Round | 4 | 1.8B | 1803 | 5 CJY A51 | ||
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Immuno-Biological Laborat... | - | Supplying valuable antibodies to save people fighting against diseases all over... | IBL originates from Japan who is an Antibody and ELISA manufacturer for worldwid... | - |
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- | Japan (HQ) | 1982 | Biotechnology, Health Care +1 | - |
1
Low
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6
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6.7K (-30%) | 8 years ago | Post Ipo Debt | 1 | 1.4B | 3199 | 5 months ago | ||
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CYBO | - | Cytometry Innovates | CYBO is an engineering company that develops innovative cytometry and cell sorti... | - |
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- | Japan (HQ) | 2018 | Biotechnology, Life Sciences | - |
1
Low
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21
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1.1K | 1 year ago | Series A | 2 | 460.0M | 511 | 6 months ago | ||
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Lily MedTech Inc. | - | Toward a world without a need to ”Fight against breast cancer” | We are a Japanese startup whose mission is” Toward a world without the phrase ‘F... | - |
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- | Japan (HQ) | 2016 | Biotechnology, Care Economy +1 | [email protected] |
1
Low
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5
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517 (-100%) | 4 years ago | Grant | 4 | 2.2B | 68 | 5 DwY u1w | ||
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ClinCloud Ltd. | - | クリンクラウドは、臨床試験の情報を収集するためのクラウドソリューションを提供する... | We are a software service provider who implements the solutions for collecting c... | - |
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- | Japan (HQ) | 2014 | Biotechnology, Health Care +1 | - |
1
Low
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3
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1.5K (36%) | 5 years ago | Corporate Round | 2 | 80.0M | 6 | 4 T9u aWA | ||
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Setsuro Tech Inc. | - | Setsuro Tech Inc. is a startup specializing in genome editing technologies, aimi... | Seturotech, Inc. is a biotech startup founded in 2017 by Tatsuya Takemoto and hi... | - |
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- | Japan (HQ) | 2017 | Biotechnology | - |
1
Low
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2
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12.5K (-21%) | 4 years ago | Series Unknown | 4 | 561.7M | 93 | 6 3Xx XYU | ||
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Cellusion Inc. | - | Regenerating Human Potential. More Freedom and More Smiles to the World. | Nihonbashi-Kobuna, Chuo-ku, Tokyo, Japan | - |
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- | Japan (HQ) | 2015 | Biotechnology, Health Care | - |
1
Low
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15
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3.5K (-63%) | 1 year ago | Series C | 4 | 4.4B | 456 | 6 months ago | ||
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CellFiber | - | Cell Culture Reimagined | CellFiber® is a Tokyo-based startup established in 2015, rooted in proprietorial... | - |
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- | Japan (HQ) | 2015 | Biotechnology, Medical Devices | [email protected] |
1
Low
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10
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994 (-100%) | 1 year ago | Series A | 4 | 9.6M | 938 | 5 months ago | ||
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KAICO Ltd. | - | Change the World with Silkworms | KAICO is a Japanese biotechnology start-up from Kyushu University, a national un... | - |
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- | Japan (HQ) | 2018 | Biotechnology, Pharmaceutical | [email protected] |
1
Low
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7
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6.4K (52%) | 1 year ago | Series A | 3 | 590.0M | 33 | 10 months ago | ||
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Fujirebio | - | A proven pioneer and partner to the diagnostics industry. | Fujirebio is is a global leader in the field of high-quality in vitro diagnostic... | - |
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- | Japan (HQ) + 14 | 1985 | Biotechnology, Health Care | - |
1
Low
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726
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24.8K (18%) | - | Series Unknown | - | 8.0M | 12237 | 6 months ago | ||
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Ac-Planta Inc. | - | Agri-biotech venture from Japan that aims to solve global food and environmental... | Ac-Planta Inc. is a RIKEN venture company founded on the basis of a technology d... | - |
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- | Japan (HQ) | 2018 | Agriculture, Biotechnology +2 | [email protected] |
1
Low
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7
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1.6K (-6%) | 1 year ago | Series A | 6 | 710.4M | 2 | 10 months ago | ||
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AlphaNavi Pharma Inc. | - | AlphaNavi Pharma is developing a unique voltage-gated sodium channel inhibitor f... | AlphaNavi Pharma is developing a potent and selective voltage-gated sodium chann... | - |
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- | Japan (HQ) | 2019 | Biotechnology, Health Care +1 | - |
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Low
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4
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514 (9%) | 6 years ago | Series A | 1 | 900.0M | 25 | 2 RhE GTc | ||
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Alivexis, Inc | - | Delivering the future of medicines | Alivexis, Inc. (formerly Modulus Discovery, Inc) is a technology-driven drug dis... | - |
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- | Japan (HQ) + 1 | 2016 | Biotechnology, Pharmaceutical | - |
1
Low
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16
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1.1K | - | Series C | - | 53.1M | 312 | 5 months ago | ||
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MUSCA Inc. | - | Circle to The Future with Insect Tech #biotech#agriculture#circulareconomy#waste... |
“Zero-Waste Nutrient Cycling in 1 Week” Insect technology firm, MUSCA, has sele... |
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- | Japan (HQ) | 2016 | Agriculture, Biotechnology +1 | [email protected] |
1
Low
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1
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18134 | - | Corporate Round | - | 1.0B | 244 | 9 tK1 4Vk | ||
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Reborna Biosciences, Inc. | - | Save the life of rare disease patients and the parents by RNA binding molecules. | Reborna Biosciences is a Japan based startup company developing RNA-targeting sm... | - |
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- | Japan (HQ) | 2018 | Biotechnology, Health Care | - |
1
Low
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7
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696 (37%) | 6 years ago | Seed | 1 | 256.0M | 77 | 5 vM6 vSa | ||
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Fermelanta, Inc. | - | A Japan-based startup that makes plant-based chemicals by synthetic biology | Fermelanta is a Japan-based biotech company that makes beneficial plant-based ch... | - |
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- | Japan (HQ) | 2022 | Biotechnology, Life Sciences | [email protected] |
1
Low
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12
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267 (-100%) | 2 years ago | Seed | 1 | 1.4M | 308 | 5 months ago | ||
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MOLCURE Inc. | - | We are an AI company focusing on accelerating drug discovery & design. | MOLCURE was founded in 2013 with a mission to build the best platform for biolog... | - |
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- | Japan (HQ) | 2013 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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29
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92455 | 3 years ago | Series C | 6 | 12.0M | 574 | 5 months ago | ||
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Preferred Networks, Inc. | - | - | Preferred Networks (PFN) was established in March 2014 with the goal to develop... | - |
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- | Japan (HQ) | 2014 | AI, Biotechnology +3 | - |
1
Low
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281
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63.1K (52%) | 5 years ago | Series Unknown | 8 | 16.5B | 4210 | 5 months ago | ||
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Anaeropharma Science, Inc... | - | - | Anaeropharma Science was established in 2004 to pioneer the development of novel... | - |
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- | Japan (HQ) | 2004 | Biopharma, Biotechnology +2 | [email protected] |
1
Low
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5
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992 | 5 years ago | Series Unknown | 5 | 49.2M | 41 | 6 mVj Uwt | ||
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NUProtein | - | 3000x cost effective cell-free protein synthesis from edible wheat germ for cult... | /n(y)ūˡ prō tēin /n.1 a company providing plant-based low-cost growth factors fo... | - |
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- | Japan (HQ) | 2016 | Biotechnology, Health and Wellness | [email protected] |
1
Low
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2
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95226 | - | Seed | - | 1.0M | 139 | 8 T50 Joc | ||
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Nanotis Corporation | - | Next Generation Testing Technology Platform | Next Generation Testing Technology Platform | - |
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- | Japan (HQ) | 2016 | Biotechnology, Care Economy +1 | [email protected] |
1
Low
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3
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89432 | - | Non Equity Assistance | - | 125.0M | 35 | 6 months ago |