Top Biopharma Startups in United States (2025 Update)
Explore the best Biopharma companies in United States. Discover high-growth startups and investment opportunities in our 2025 updated list.
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Explore Top Biopharma Startups in United States featuring 678 Companies
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Urovant Sciences | - | is part of Sumitomo Pharma America as of July 2023 | This page is no longer active or monitored. We are now Sumitomo Pharma America (... | - |
United States
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Irvine | United States (HQ) + 1 | 2017 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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97
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230 | 6 years ago | Debt Financing | 1 | 100.0M | 11957 | 1 year ago | |
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Ginkgo Bioworks, Inc. | - | Making biology easier to engineer. | At Ginkgo, we use biology to grow the future. Companies across industries levera... | - |
United States
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Boston | United States (HQ) + 3 | 2009 | Biopharma, Biotechnology | [email protected] |
1
Low
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1012
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67.6K (2%) | 1 year ago | Grant | 14 | 1.6B | 94557 | 5 months ago | |
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Roivant | - | Reinventing Biopharma | Roivant aims to improve health by rapidly delivering innovative medicines and te... | - |
United States
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New York | United States (HQ) + 2 | 2014 | Biopharma, Biotechnology +2 | [email protected] |
1
Low
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256
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22.4K (2%) | 2 years ago | Post Ipo Equity | 7 | 2.5B | 29023 | 4 months ago | |
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Ocugen | - | Approaching healthcare innovation with purpose and agility to deliver new breakt... | Ocugen, Inc. is a biotechnology company focused on discovering, developing, and... | - |
United States
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Malvern | United States (HQ) | 2013 | Biopharma, Biotechnology +1 | - |
1
Low
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87
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29.1K | 6 months ago | Post Ipo Debt | 8 | 271.5M | 14544 | 2 months ago | |
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Aurion Biotech | - | We're on a mission to cure blindness with our transformational platform of advan... | Aurion Biotech is a clinical stage biotech company, developing a transformationa... | - |
United States
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Seattle | United States (HQ) + 1 | 2022 | Biopharma, Biotechnology +1 | - |
1
Low
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72
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558 (-100%) | 3 years ago | Series Unknown | 1 | 120.0M | 5173 | 5 months ago | |
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CymaBay Therapeutics | - | Dedicated to improving the lives of patients with liver diseases | We are a clinical-stage biopharmaceutical company focused on developing and prov... | - |
United States
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Newark | United States (HQ) | 1991 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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66
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2.0K (-57%) | 1 year ago | Post Ipo Equity | 15 | 854.2M | 13203 | 10 months ago | |
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Cytokinetics | - | Empowering Muscle Empowering Lives | Cytokinetics is a late-stage biopharmaceutical company focused on discovering, d... | - |
United States
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South San Francisco | United States (HQ) | 1998 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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540
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162 (-100%) | 1 year ago | Post Ipo Equity | 11 | 1.8B | 27563 | 6 months ago | |
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REGENXBIO | - | Seeking to improve lives through the curative potential of gene therapy. | REGENXBIO is a leading clinical-stage biotechnology company seeking to improve l... | - |
United States
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Rockville | United States (HQ) | 2008 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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366
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14.5K (-1%) | 1 year ago | Post Ipo Equity | 10 | 778.2M | 34148 | 5 months ago | |
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HiRO - Harvest Integrated... | - | Become the hero in innovative drug development | Harvest Integrated Research Organization (HiRO) is a globally oriented, innovati... | - |
United States
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Somerset | United States (HQ) | 2020 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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78
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1.5K (36%) | 3 years ago | Series A | 1 | 10.0M | 5875 | 5 months ago | |
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T&L Biotechnology | - | Provide One-Stop Products and Services for CGT Research | T&L Biotechnology Ltd. focuses on the research and development of upstream, GMP-... | - |
United States
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Carlsbad | United States (HQ) + 1 | 2011 | Biopharma, Biotechnology | - |
1
Low
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12
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263 | 2 years ago | Series A | 1 | 90.0M | 2481 | 4 months ago | |
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Avalyn Pharma | - | Targeted therapies for rare lung diseases | Avalyn is a clinical-stage biopharmaceutical company developing inhaled therapie... | - |
United States
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Cambridge | United States (HQ) | 2011 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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39
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2.1K (-55%) | 1 year ago | Series C | 3 | 272.5M | 4295 | 5 months ago | |
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Arcellx | - | We're a clinical-stage biotech company reimagining cell therapy through the deve... | We are a clinical-stage biotechnology company reimagining cell therapy through t... | - |
United States
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Redwood City | United States (HQ) | 2015 | Biopharma, Biotechnology +3 | [email protected] |
1
Low
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176
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12.5K (84%) | 1 year ago | Post Ipo Equity | 7 | 622.0M | 14684 | 5 months ago | |
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Onconova Therapeutics | - | Onconova is focused on discovering and developing novel products for patients wi... | Onconova Therapeutics, Inc. (NASDAQ: ONTX) is a clinical-stage biopharmaceutical... | - |
United States
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Newtown | United States (HQ) | 1998 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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23
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1.7K (31%) | 3 years ago | Post Ipo Equity | 11 | 177.9M | 3589 | 1 year ago | |
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Ganymede | - | Ganymede is the modern cloud data platform for the life sciences and manufacturi... | Ganymede liberates your data by connecting your instruments, your LIMS, and your... | - |
United States
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Palo Alto | United States (HQ) | 2022 | Biopharma, Enterprise Software +1 | [email protected] |
1
Low
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56
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17 (-100%) | 2 years ago | Series A | 2 | 15.7M | 9630 | 5 months ago | |
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PrognomiQ Inc | - | Transform healthcare and early disease detection through the power of multi-omic... | PrognomiQ aims to generate proteomic information with high accuracy, scale and s... | - |
United States
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San Mateo | United States (HQ) | 2020 | Biopharma, Biotechnology +2 | [email protected] |
1
Low
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58
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2.2K (174%) | 3 years ago | Series Unknown | 2 | 101.0M | 7296 | 6 months ago | |
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APTIMMUNE BIOLOGICS, INC. | - | Aptimmune specializes in developing revolutionary mucosal vaccines, made with Ba... | Aptimmune Biologics specializes in developing revolutionary mucosal vaccines tha... | - |
United States
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Saint Louis | United States (HQ) + 1 | 2010 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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5
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76 | 3 years ago | Convertible Note | 5 | 8.9M | 242 | 1 year ago | |
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Outlook Therapeutics, Inc... | - | ONS-5010: A uniquely positioned anti-VEGF therapy for wet AMD, DME and BRVO | Outlook Therapeutics is a late clinical-stage biopharmaceutical company working... | - |
United States
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Cranbury | United States (HQ) | 2011 | Biopharma, Biotechnology +2 | [email protected] |
1
Low
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44
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2.6K | 1 year ago | Post Ipo Equity | 13 | 340.3M | 9985 | 5 months ago | |
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Bloom Science, Inc. | - | Leveraging the Gut-Brain Axis to Drive Therapeutic Innovation | Bloom Science is a clinical-stage, central nervous system (CNS) company, trailbl... | - |
United States
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San Diego | United States (HQ) | 2018 | Biopharma, Biotechnology | [email protected] |
1
Low
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20
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37 (-100%) | 3 years ago | Series A | 3 | 12.0M | 2830 | 5 months ago | |
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Cleave Therapeutics, Inc.... | - | VCP/p97 Inhibitors for Oncology and Neurodegenerative Diseases | Cleave Therapeutics is a biopharmaceutical company focused on valosin-containing... | - |
United States
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San Francisco | United States (HQ) | 2011 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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2
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602 | 5 years ago | Series C | 4 | 101.0M | 1208 | 1 year ago | |
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Life Magnetics | - | Where The Stability of RNA Is No Longer a Limiting Factor. | Processing raw biological samples is one of the most difficult problems in life... | - |
United States
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Plymouth | United States (HQ) | 2013 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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5
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1.3K (181%) | 5 years ago | Series Unknown | 5 | 732.0K | 322 | 8 months ago | |
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Xilio Therapeutics, Inc. | - | Focused on harnessing the immune system to achieve deep and durable clinical res... | Xilio is a Waltham, Massachusetts-based clinical-stage biopharmaceutical company... | - |
United States
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Waltham | United States (HQ) | 2016 | Biopharma, Biotechnology +2 | - |
1
Low
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71
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3.6K (-63%) | 1 year ago | Post Ipo Equity | 5 | 244.3M | 8379 | 5 months ago | |
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NOVOS | - | Making the latest scientific advances in longevity accessible and achievable for... | NOVOS leverages science and data to create the best nutraceuticals to extend hum... | - |
United States
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New York | United States (HQ) | 2018 | Biopharma, Biotechnology +5 | [email protected] |
1
Low
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30
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300.5K (-18%) | 3 years ago | Angel | 3 | 3.2M | 9821 | 5 months ago | |
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Keystone Dental Group | - | We develop, acquire and commercialize oral healthcare technologies that improve... | Keystone Dental Group is an oral healthcare company combining Keystone Dental In... | - |
United States
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Burlington | United States (HQ) + 2 | 2006 | Biopharma, Health Care +1 | - |
1
Low
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216
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8.6K (-29%) | 3 years ago | Series Unknown | 3 | 54.7M | 8965 | 5 months ago | |
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Tierra Biosciences | - | Speed, scale, and simplicity with protein on-demand | Tierra Biosciences is a synthetic biology company that accelerates the pace of d... | - |
United States
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San Leandro | United States (HQ) | 2015 | AI, Biopharma +2 | [email protected] |
1
Low
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24
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3.8K (245%) | 1 year ago | Series A | 6 | 36.6M | 4517 | 6 months ago | |
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Halo Labs | - | Low Volume High-Throughput Cell, Gene, and Protein Therapeutic Quality | We help our customers reduce development time and improve patient safety by quan... | - |
United States
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Burlingame | United States (HQ) | 2011 | Analytics, Biopharma +3 | [email protected] |
1
Low
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29
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3.5K (6%) | 2 years ago | Series C | 10 | 26.8M | 3910 | 5 months ago | |
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Ocuphire Pharma | - | Restoring Vision and Clarity | We are a late-stage ophthalmic biopharmaceutical company focused on developing a... | - |
United States
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Farmington Hills | United States (HQ) | 2018 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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15
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5.1K (-24%) | 3 years ago | Post Ipo Equity | 5 | 24.6M | 4550 | 7 months ago | |
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Enlaza Therapeutics | - | Pioneering Covalent Biologics | Enlaza Therapeutics is pioneering the field of covalent biologics. These novel c... | - |
United States
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San Diego | United States (HQ) | 2020 | Biopharma, Biotechnology +2 | - |
1
Low
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54
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1.6K (-27%) | 1 year ago | Series A | 2 | 161.0M | 4538 | 6 months ago | |
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Satellite Bio | - | Tackling some of humankind’s most elusive diseases with Tissue Therapeutics, a n... | At Satellite Bio, we’re on a journey – a quest to treat some of the most elusive... | - |
United States
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Cambridge | United States (HQ) | 2019 | Biopharma, Biotechnology | - |
1
Low
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34
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1.2K (9%) | 3 years ago | Series A | 2 | 101.5M | 7313 | 9 months ago | |
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Humonix Biosciences, Inc. | - | Accelerating and de-risking ophthalmic drug development | Humonix Biosciences is a specialty pharma research company that uses an innovati... | - |
United States
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Albany | United States (HQ) | 2015 | Biopharma, Biotechnology +1 | - |
1
Low
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12
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650 | - | Seed | - | 2.2M | 719 | 5 months ago | |
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HDT Bio | - | Immune Therapy For All | HDT Bio is a vaccine and immunotherapy Biotechnology company developing drugs fo... | - |
United States
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Seattle | United States (HQ) | 2018 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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58
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2.9K (26%) | 1 year ago | Grant | 7 | 70.0M | 5663 | 5 months ago | |
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Evofem Biosciences | - | Developing and commercializing products that address unmet needs in women’s sexu... | Evofem Biosciences, Inc., (OTCQB: EVFM) is a commercial-stage biopharmaceutical... | - |
United States
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San Diego | United States (HQ) | 2015 | Biopharma, Health Care +1 | [email protected] |
1
Low
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43
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4.0K (38%) | 1 year ago | Post Ipo Equity | 15 | 471.8M | 9507 | 6 months ago | |
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Stabilux Biosciences, Inc... | - | Detect the undetectable | New biomedical discovery is driving the need to find improved methods to identif... | - |
United States
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Ann Arbor | United States (HQ) + 1 | 2014 | Biopharma, Biotechnology | - |
1
Low
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10
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699 | 4 years ago | Grant | 4 | 1.9M | 117 | 5 months ago | |
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Poseida Therapeutics, Inc... | - | The Capacity to Cure | Poseida Therapeutics is a clinical-stage biopharmaceutical company advancing dif... | - |
United States
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San Diego | United States (HQ) | 2014 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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349
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6.6K (57%) | 1 year ago | Post Ipo Equity | 9 | 460.5M | 40739 | 5 months ago | |
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Tetraphase Pharmaceutical... | - | Fighting against antimicrobial resistance is at the core of our technology and o... | Tetraphase is fighting one of the most significant threats to humanity — antibio... | - |
United States
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Watertown | United States (HQ) | 2006 | Biopharma, Biotechnology +1 | - |
1
Low
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14
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28 | 8 years ago | Grant | 7 | 99.0M | 3888 | 1 ajK NJQ | |
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AeroSafe Global | - | The proven end-to-end solution for the biopharma industry and its mission-critic... | AeroSafe Global provides the most reliable, simple and sustainable temperature s... | - |
United States
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Rochester | United States (HQ) | 1995 | Biopharma, Logistics +2 | [email protected] |
1
Low
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109
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1.5K (-59%) | 1 year ago | Private Equity | 12 | 162.7M | 3610 | 5 months ago | |
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Ansun Biopharma, Inc. | - | Discovering solutions for the world | Ansun Biopharma is a late-stage clinical development company dedicated to saving... | - |
United States
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San Diego | United States (HQ) | 2003 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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20
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986 (43%) | 5 years ago | Series B | 7 | 213.1M | 2004 | 6 H8G JUf | |
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NGM Biopharmaceuticals | - | Explorers on the frontier of life-changing science. | NGM Bio is a biopharmaceutical company focused on discovering and developing nov... | - |
United States
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South San Francisco | United States (HQ) | 2008 | Biopharma, Biotechnology | [email protected] |
1
Low
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157
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3.9K (3%) | 10 months ago | Series A | 7 | 542.4M | 9694 | 5 months ago | |
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Teon Therapeutics Inc. | - | Teon is a clinical company targeting metabolic signaling pathways and pioneering... | Teon is a clinical-stage company targeting metabolic signaling pathways and pion... | - |
United States
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Redwood City | United States (HQ) | 2017 | Biopharma, Biotechnology +2 | [email protected] |
1
Low
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6
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596 (226%) | 4 years ago | Series A | 2 | 37.0M | 1094 | 4 gyd 9Zj | |
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Be Biopharma | - | Engineered B cells as medicines | Be Bio is pioneering Engineered B Cell Medicines (BCMs) to dramatically improve... | - |
United States
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Cambridge | United States (HQ) | 2020 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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96
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6.5K (124%) | 3 years ago | Series B | 2 | 182.0M | 7502 | 5 months ago | |
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OrsoBio | - | Advancing first-in-class therapies to restore energy homeostasis | OrsoBio, Inc. is a privately held, clinical-stage biopharmaceutical company dedi... | - |
United States
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Palo Alto | United States (HQ) | 2021 | Biopharma, Biotechnology +1 | [email protected] |
1
Low
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19
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2.4K (301%) | 1 year ago | Series A | 2 | 62.3M | 2200 | 6 months ago |