Top B2B Startups in United States (2025 Update)

Explore the best B2B companies in United States. Discover high-growth startups and investment opportunities in our 2025 updated list.

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Explore Top B2B Startups in United States featuring 1981 Companies

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Pixels Design Agency (PDA... - Let us help you build the perfect digital product with our top-notch design skil... Pixels Design Agency is a full-stack web and mobile design and development compa... - United States Flag United States Morton Grove United States (HQ) 2018 Advertising, Applications +3 -
1
Low
6
2619 - Series A - 1.0K 44222 1 l11 VgG
momentor - Momentum turns the MOUNTAINS of data captured on every sales calls into highly a... Momentum uses AI and automation to capture and extracts insights from customer i... - United States Flag United States San Francisco United States (HQ) + 3 2019 B2B, Information Technology +1 -
1
Low
47
427 (-100%) 3 years ago Seed 1 5.0M 3260 1 year ago
Chili Piper - The Secret Spice of Top Revenue Teams 🌶 Chili Piper is the all-in-one Demand Conversion Platform, used by Intuit, Spotif... - United States Flag United States New York United States (HQ) 2016 Analytics, B2B +4 [email protected]
1
Low
251
593.6K (3%) 4 years ago Secondary Market 6 54.4M 76414 2 months ago
Cien.ai - Measure What Matters Cien.ai is a data analytics platform using AI to generate actionable insights fr... - United States Flag United States Dallas United States (HQ) + 2 2016 AI, Analytics +4 [email protected]
1
Low
14
1.2K (-40%) 6 years ago Seed 3 5.7M 2173 5 months ago
Leverice - Leverice is the only deep-threaded, structured messaging platform that lets your... Say goodbye to chaos in your team communications. Leverice is the only deep-thre... - United States Flag United States San Jose United States (HQ) 2018 B2B, Messaging +2 [email protected]
1
Low
6
837 (-100%) 6 years ago Pre Seed 1 600.0K 378 3 years ago
Nifty Learning - Operational Intelligence for Learning & Development Nifty Learning is the only command center for Enterprise L&D Teams.

We automate...
- United States Flag United States Dover United States (HQ) 2021 B2B, EdTech +3 [email protected]
1
Low
7
517 (-100%) 4 years ago Convertible Note 3 272.0K 816 8 months ago
Yuvod - Connecting guests to the content they love! Yuvod Hotel TV solution, gives guests the ability to access their favorite conte... - United States Flag United States Miami United States (HQ) 2019 B2B, Media -
1
Low
23
89 (-100%) 2 years ago Seed 2 4.0M 1778 5 months ago
Automile - Automile, an IoT company, provides real-time gps tracking and management of flee... Automile, an IoT company, provides real-time gps tracking and management of flee... - United States Flag United States Pleasant Grove United States (HQ) + 2 2014 API, B2B +2 [email protected]
1
Low
24
80.6K (-4%) 7 years ago Series B 4 47.3M 1619 5 years ago
PromoRepublic - One marketing platform for franchise growth. PromoRepublic's marketing platform helps franchises grow their online visibility... - United States Flag United States Palo Alto United States (HQ) + 1 2014 Advertising, B2B +4 [email protected]
1
Low
60
55.7K (-29%) 3 years ago Convertible Note 9 3.3M 3026 5 months ago
ApexQubit - ApexQubit is a biotechnology company that is harnessing frontier technologies fo... ApexQubit is a biotechnology company that is harnessing frontier technologies fo... - United States Flag United States Berkeley United States (HQ) 2018 B2B, Biotechnology +6 [email protected]
1
Low
1
625 4 years ago Non Equity Assistance 6 430.5K 641 5 G9P r0i
Jobicy – Remote Jobs - Remote, work from home, and flexible job opportunities. Jobicy is an online platform dedicated to connecting talented people who seek re... - United States Flag United States New York United States (HQ) + 1 2021 B2B, Computing +2 -
1
Low
2
119.4K 3 years ago Post Ipo Debt 2 151.2K 1403 10 months ago
Sequence - Automate billing for every custom contract Sequence is the modern billing, CPQ and revrec platform to unlock error-free rev... - United States Flag United States New York United States (HQ) + 1 2021 B2B -
1
Low
44
5.0K (16%) 4 years ago Seed 1 16.6M 4767 4 months ago
Upflow - Get paid faster, enjoy better customer relationships AND realize your full growt... Upflow is a Financial Relationship Management solution that helps our customers... - United States Flag United States New York United States (HQ) + 1 2018 B2B, Financial Services +4 [email protected]
1
Low
72
48.5K (-17%) 1 year ago Series A 7 22.9M 6285 6 months ago
Tranch - B2B Checkout with Pay Now and Pay Later. Tranch is the invoice to payments platform for enterprises who want to optimize... - United States Flag United States New York United States (HQ) 2021 B2B, Financial Services +3 [email protected]
1
Low
14
4.8K 1 year ago Seed 5 104.4M 3903 5 months ago
Luna.ai - The only AI prospecting tool that outperforms humans The old sales playbook is broken. Today's prospects have zero patience for those... - United States Flag United States Palo Alto United States (HQ) 2016 AI, Automation +5 [email protected]
1
Low
39
52.9K 1 year ago Pre Seed 2 5.0M 2431 6 months ago
Wellbees - Employee Wellbeing Platform Wellbees is an employee wellbeing company reaching 60+% active usage rate throug... - United States Flag United States Wilmington United States (HQ) + 3 2013 B2B, Health and Wellness +2 [email protected]
1
Low
113
3.2K 1 year ago Convertible Note 3 3.2M 14958 5 months ago
Werk - Remote and Hybrid collaboration toolkit to the new era Werk is a collaboration tool designed for remote and hybrid teams. In different... - United States Flag United States San Francisco United States (HQ) 2020 Analytics, B2B +3 [email protected]
1
Low
225
437 3 years ago Pre Seed 1 150.0K 22440 2 years ago
Unbabel - Unbabel helps businesses deliver multilingual customer experience at scale. Unbabel eliminates language barriers so that businesses can thrive across cultur... - United States Flag United States San Francisco United States (HQ) + 4 2013 AI, B2B +1 [email protected]
1
Low
817
166.2K 5 years ago Series C 7 91.2M 40449 3 months ago
Monetizr - The world’s most advanced in-game ad experience platform where brands reach and... Monetizr is an in-game ad experience platform integrating brand stories at scale... - United States Flag United States Atlanta United States (HQ) + 1 2016 Advertising, B2B +5 -
1
Low
26
927 1 year ago Seed 2 4.2M 986 1 year ago
StructionSite (acquired b... Not active anymore Capture photo documentation of your jobs in 360-degrees and take your image sear... Launched in 2016 and acquired by DroneDeploy in 2022, StructionSite is a leading... - United States Flag United States Oakland United States (HQ) 2016 AI, B2B +4 [email protected]
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N/A
8
11.7K (-47%) 3 years ago Series Unknown 5 18.5M 11056 8 months ago
Argus - Argus automates employee trade compliance process, reducing risk and saving time... Argus offers a comprehensive solution by automating the entire employee trade co... - United States Flag United States New York United States (HQ) 2021 B2B, Fintech -
1
Low
25
576 2 years ago Seed 2 2.9M 849 11 months ago
Clearbit - Hit your target, in any market. Get started at clearbit.com. Clearbit helps companies create, capture, and convert demand from ideal customer... - United States Flag United States San Francisco United States (HQ) 2015 API, Analytics +1 [email protected]
1
Low
19
288.5K 6 years ago Series A 2 17.0M 16943 1 year ago
Ocean.io - Growth happens when you prioritize the right accounts 🎯 B2B GTM teams use Ocean.io's prospecting data platform to find accounts and cont... - United States Flag United States San Francisco United States (HQ) + 1 2017 AI, B2B +1 [email protected]
1
Low
62
91.6K 3 years ago Series A 1 6.0M 10594 3 months ago
HerHeadquarters - HerHeadquarters elevates women-owned businesses through its B2B platform, experi... HerHeadquarters is elevating women-owned businesses through its platform, woman-... - United States Flag United States Houston United States (HQ) 2019 B2B, Platforms +1 [email protected]
1
Low
4
501 (-16%) 2 years ago Pre Seed 4 225.0K 694 6 months ago
Vivun - Everything PreSales needs to operate effectively, automate demos, and drive coll... Vivun is your Sales team's Technical Copilot, helping the fastest growing compan... - United States Flag United States Oakland United States (HQ) 2018 AI, Automation +4 [email protected]
1
Low
85
26.3K (-30%) 3 years ago Series C 4 131.0M 8707 5 months ago
OneDine - OneDine® is transforming dining experiences by helping restaurants provide servi... One platform. Endless solutions. - United States Flag United States Plano United States (HQ) 2017 B2B, B2C +6 [email protected]
1
Low
23
608.4K (-24%) 5 years ago Series A 2 12.0M 2691 5 months ago
ShearShare, Inc. (acquire... - B2B marketplace that monetizes underutilized assets in the beauty & barbering in... Rent space to work anywhere for any price.

ShearShare is a B2B platform that co...
- United States Flag United States Mckinney United States (HQ) + 1 2017 B2B, Marketplaces +3 [email protected]
1
Low
10
6.2K (-35%) 3 years ago Seed 3 5.5M 1660 6 months ago
Pod Foods - We Deliver Innovation Pod Foods is a logistics-enabled, data-powered B2B marketplace for wholesale foo... - United States Flag United States San Francisco United States (HQ) 2017 B2B, Consumer Goods +5 [email protected]
1
Low
55
17.2K (11%) 3 years ago Series A 3 18.6M 11455 5 months ago
Yodel.io (acquired by Bre... - The intelligent business phone for teams that lives in Slack Make your phone calls simpler, easier to handle and more collaborative - and all... - United States Flag United States San Francisco United States (HQ) + 2 2016 B2B, SaaS +1 [email protected]
1
Low
5
19.9K (-29%) 5 years ago Pre Seed 3 1.6M 337 6 jlv ueA
R2.ai Not active anymore the AI that Helps Create AI R2.ai is the AI that helps create AI, with a mission to drive AI adoption for al... - United States Flag United States San Ramon United States (HQ) 2015 AI, Analytics +6 [email protected]
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N/A
7
638 8 years ago Seed 1 1.4M 148 4 Lki MLU
SpecCheck (YC W23) - Innovative Software For The Optical Industry SpecCheck, backed by Y Combinator (W23), is an all-in-one solution that provides... - United States Flag United States San Francisco United States (HQ) 2022 B2B, Health Care +1 [email protected]
1
Low
4
4.0K (-32%) 2 years ago Seed 1 3.7M 716 6 months ago
Tough Leaf - The Leader in Diverse Firm Procurement A platform that empowers minority and women-owned businesses to win more project... - United States Flag United States New York United States (HQ) 2020 B2B, Platforms +2 [email protected]
1
Low
21
2.1K (31%) 11 months ago Series A 3 7.8M 2556 5 months ago
Revelo - Find, hire, and pay full-time, remote engineers and developers based in Latin Am... Hire top-tier engineers based in Latin America in a matter of days. With a netwo... - United States Flag United States Miami United States (HQ) 2015 B2B, Platforms +1 [email protected]
1
Low
390
147.4K (20%) 2 years ago Series B 7 48.1M 64648 5 months ago
Full Harvest - We are the leading produce business marketplace for all produce grades, includin... Full Harvest runs the leading B2B produce marketplace that connects commercial p... - United States Flag United States San Francisco United States (HQ) 2015 Agriculture, B2B +5 [email protected]
1
Low
65
4.8K (-38%) 3 years ago Series B 8 39.5M 11677 8 months ago
CaliberMind - The leading B2B Go-To-Market Data Platform that helps you spot market trends fir... CaliberMind is a multi-touch attribution platform that exists to help B2B market... - United States Flag United States Houston United States (HQ) 2016 Analytics, Automation +1 [email protected]
1
Low
32
15.7K (162%) 3 years ago Series A 7 14.4M 9242 5 months ago
Metadata - Multi-Channel ABM Advertising Platform Metadata is a multi-channel ABM platform built to automate and optimize paid cam... - United States Flag United States San Jose United States (HQ) 2015 Advertising, B2B +2 [email protected]
1
Low
157
49.3K (-5%) 2 years ago Series Unknown 11 56.9M 24190 5 months ago
OrderCircle - OrderCircle brings the simplicity of B2C e-commerce to B2B wholesale ordering. OrderCircle is elegant e-commerce for B2B commerce - we're bringing the same all... - United States Flag United States San Francisco United States (HQ) 2015 B2B, E-Commerce +1 [email protected]
1
Low
6
6.2K (22%) 8 years ago Seed 1 125.0K 191 11 months ago
Disprz - An AI-powered right skilling suite that helps enterprises unlock business potent... Disprz is a leading provider of GenAI-powered, learning and skilling suite (LMS,... - United States Flag United States West Orange United States (HQ) + 2 2015 AI, Analytics +5 [email protected]
1
Low
289
29.4K (15%) 1 year ago Series C 9 52.4M 45570 5 months ago
Field Engineer - Field Engineer is the only On Demand marketplace with 75,000+ Engineers supporti... Fieldengineer.com (FE) is a global on-demand workforce for the telecom & system... - United States Flag United States New York United States (HQ) 2015 B2B, B2C +2 [email protected]
1
Low
170
105.3K (23%) 8 years ago Seed 2 2.5M 5986 1 year ago
Stedi - The only API-first healthcare clearinghouse Stedi allows developers to instantly automate real-time eligibility checks and c... - United States Flag United States New York United States (HQ) 2017 B2B, Information Technology [email protected]
1
Low
43
32.4K (17%) 4 years ago Series B 4 75.0M 2667 7 months ago