Top B2B Startups in United States (2025 Update)
Explore the best B2B companies in United States. Discover high-growth startups and investment opportunities in our 2025 updated list.
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Explore Top B2B Startups in United States featuring 1981 Companies
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Pixels Design Agency (PDA... | - | Let us help you build the perfect digital product with our top-notch design skil... | Pixels Design Agency is a full-stack web and mobile design and development compa... | - |
United States
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Morton Grove | United States (HQ) | 2018 | Advertising, Applications +3 | - |
1
Low
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6
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2619 | - | Series A | - | 1.0K | 44222 | 1 l11 VgG | |
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momentor | - | Momentum turns the MOUNTAINS of data captured on every sales calls into highly a... | Momentum uses AI and automation to capture and extracts insights from customer i... | - |
United States
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San Francisco | United States (HQ) + 3 | 2019 | B2B, Information Technology +1 | - |
1
Low
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47
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427 (-100%) | 3 years ago | Seed | 1 | 5.0M | 3260 | 1 year ago | |
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Chili Piper | - | The Secret Spice of Top Revenue Teams 🌶 | Chili Piper is the all-in-one Demand Conversion Platform, used by Intuit, Spotif... | - |
United States
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New York | United States (HQ) | 2016 | Analytics, B2B +4 | [email protected] |
1
Low
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251
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593.6K (3%) | 4 years ago | Secondary Market | 6 | 54.4M | 76414 | 2 months ago | |
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Cien.ai | - | Measure What Matters | Cien.ai is a data analytics platform using AI to generate actionable insights fr... | - |
United States
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Dallas | United States (HQ) + 2 | 2016 | AI, Analytics +4 | [email protected] |
1
Low
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14
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1.2K (-40%) | 6 years ago | Seed | 3 | 5.7M | 2173 | 5 months ago | |
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Leverice | - | Leverice is the only deep-threaded, structured messaging platform that lets your... | Say goodbye to chaos in your team communications. Leverice is the only deep-thre... | - |
United States
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San Jose | United States (HQ) | 2018 | B2B, Messaging +2 | [email protected] |
1
Low
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6
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837 (-100%) | 6 years ago | Pre Seed | 1 | 600.0K | 378 | 3 years ago | |
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Nifty Learning | - | Operational Intelligence for Learning & Development |
Nifty Learning is the only command center for Enterprise L&D Teams. We automate... |
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United States
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Dover | United States (HQ) | 2021 | B2B, EdTech +3 | [email protected] |
1
Low
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7
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517 (-100%) | 4 years ago | Convertible Note | 3 | 272.0K | 816 | 8 months ago | |
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Yuvod | - | Connecting guests to the content they love! | Yuvod Hotel TV solution, gives guests the ability to access their favorite conte... | - |
United States
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Miami | United States (HQ) | 2019 | B2B, Media | - |
1
Low
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23
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89 (-100%) | 2 years ago | Seed | 2 | 4.0M | 1778 | 5 months ago | |
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Automile | - | Automile, an IoT company, provides real-time gps tracking and management of flee... | Automile, an IoT company, provides real-time gps tracking and management of flee... | - |
United States
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Pleasant Grove | United States (HQ) + 2 | 2014 | API, B2B +2 | [email protected] |
1
Low
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24
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80.6K (-4%) | 7 years ago | Series B | 4 | 47.3M | 1619 | 5 years ago | |
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PromoRepublic | - | One marketing platform for franchise growth. | PromoRepublic's marketing platform helps franchises grow their online visibility... | - |
United States
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Palo Alto | United States (HQ) + 1 | 2014 | Advertising, B2B +4 | [email protected] |
1
Low
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60
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55.7K (-29%) | 3 years ago | Convertible Note | 9 | 3.3M | 3026 | 5 months ago | |
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ApexQubit | - | ApexQubit is a biotechnology company that is harnessing frontier technologies fo... | ApexQubit is a biotechnology company that is harnessing frontier technologies fo... | - |
United States
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Berkeley | United States (HQ) | 2018 | B2B, Biotechnology +6 | [email protected] |
1
Low
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1
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625 | 4 years ago | Non Equity Assistance | 6 | 430.5K | 641 | 5 G9P r0i | |
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Jobicy – Remote Jobs | - | Remote, work from home, and flexible job opportunities. | Jobicy is an online platform dedicated to connecting talented people who seek re... | - |
United States
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New York | United States (HQ) + 1 | 2021 | B2B, Computing +2 | - |
1
Low
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2
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119.4K | 3 years ago | Post Ipo Debt | 2 | 151.2K | 1403 | 10 months ago | |
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Sequence | - | Automate billing for every custom contract | Sequence is the modern billing, CPQ and revrec platform to unlock error-free rev... | - |
United States
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New York | United States (HQ) + 1 | 2021 | B2B | - |
1
Low
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44
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5.0K (16%) | 4 years ago | Seed | 1 | 16.6M | 4767 | 4 months ago | |
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Upflow | - | Get paid faster, enjoy better customer relationships AND realize your full growt... | Upflow is a Financial Relationship Management solution that helps our customers... | - |
United States
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New York | United States (HQ) + 1 | 2018 | B2B, Financial Services +4 | [email protected] |
1
Low
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72
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48.5K (-17%) | 1 year ago | Series A | 7 | 22.9M | 6285 | 6 months ago | |
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Tranch | - | B2B Checkout with Pay Now and Pay Later. | Tranch is the invoice to payments platform for enterprises who want to optimize... | - |
United States
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New York | United States (HQ) | 2021 | B2B, Financial Services +3 | [email protected] |
1
Low
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14
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4.8K | 1 year ago | Seed | 5 | 104.4M | 3903 | 5 months ago | |
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Luna.ai | - | The only AI prospecting tool that outperforms humans | The old sales playbook is broken. Today's prospects have zero patience for those... | - |
United States
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Palo Alto | United States (HQ) | 2016 | AI, Automation +5 | [email protected] |
1
Low
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39
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52.9K | 1 year ago | Pre Seed | 2 | 5.0M | 2431 | 6 months ago | |
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Wellbees | - | Employee Wellbeing Platform | Wellbees is an employee wellbeing company reaching 60+% active usage rate throug... | - |
United States
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Wilmington | United States (HQ) + 3 | 2013 | B2B, Health and Wellness +2 | [email protected] |
1
Low
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113
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3.2K | 1 year ago | Convertible Note | 3 | 3.2M | 14958 | 5 months ago | |
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Werk | - | Remote and Hybrid collaboration toolkit to the new era | Werk is a collaboration tool designed for remote and hybrid teams. In different... | - |
United States
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San Francisco | United States (HQ) | 2020 | Analytics, B2B +3 | [email protected] |
1
Low
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225
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437 | 3 years ago | Pre Seed | 1 | 150.0K | 22440 | 2 years ago | |
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Unbabel | - | Unbabel helps businesses deliver multilingual customer experience at scale. | Unbabel eliminates language barriers so that businesses can thrive across cultur... | - |
United States
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San Francisco | United States (HQ) + 4 | 2013 | AI, B2B +1 | [email protected] |
1
Low
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817
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166.2K | 5 years ago | Series C | 7 | 91.2M | 40449 | 3 months ago | |
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Monetizr | - | The world’s most advanced in-game ad experience platform where brands reach and... | Monetizr is an in-game ad experience platform integrating brand stories at scale... | - |
United States
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Atlanta | United States (HQ) + 1 | 2016 | Advertising, B2B +5 | - |
1
Low
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26
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927 | 1 year ago | Seed | 2 | 4.2M | 986 | 1 year ago | |
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StructionSite (acquired b... | Not active anymore | Capture photo documentation of your jobs in 360-degrees and take your image sear... | Launched in 2016 and acquired by DroneDeploy in 2022, StructionSite is a leading... | - |
United States
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Oakland | United States (HQ) | 2016 | AI, B2B +4 | [email protected] |
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N/A
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8
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11.7K (-47%) | 3 years ago | Series Unknown | 5 | 18.5M | 11056 | 8 months ago | |
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Argus | - | Argus automates employee trade compliance process, reducing risk and saving time... | Argus offers a comprehensive solution by automating the entire employee trade co... | - |
United States
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New York | United States (HQ) | 2021 | B2B, Fintech | - |
1
Low
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25
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576 | 2 years ago | Seed | 2 | 2.9M | 849 | 11 months ago | |
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Clearbit | - | Hit your target, in any market. Get started at clearbit.com. | Clearbit helps companies create, capture, and convert demand from ideal customer... | - |
United States
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San Francisco | United States (HQ) | 2015 | API, Analytics +1 | [email protected] |
1
Low
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19
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288.5K | 6 years ago | Series A | 2 | 17.0M | 16943 | 1 year ago | |
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Ocean.io | - | Growth happens when you prioritize the right accounts 🎯 | B2B GTM teams use Ocean.io's prospecting data platform to find accounts and cont... | - |
United States
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San Francisco | United States (HQ) + 1 | 2017 | AI, B2B +1 | [email protected] |
1
Low
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62
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91.6K | 3 years ago | Series A | 1 | 6.0M | 10594 | 3 months ago | |
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HerHeadquarters | - | HerHeadquarters elevates women-owned businesses through its B2B platform, experi... | HerHeadquarters is elevating women-owned businesses through its platform, woman-... | - |
United States
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Houston | United States (HQ) | 2019 | B2B, Platforms +1 | [email protected] |
1
Low
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4
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501 (-16%) | 2 years ago | Pre Seed | 4 | 225.0K | 694 | 6 months ago | |
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Vivun | - | Everything PreSales needs to operate effectively, automate demos, and drive coll... | Vivun is your Sales team's Technical Copilot, helping the fastest growing compan... | - |
United States
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Oakland | United States (HQ) | 2018 | AI, Automation +4 | [email protected] |
1
Low
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85
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26.3K (-30%) | 3 years ago | Series C | 4 | 131.0M | 8707 | 5 months ago | |
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OneDine | - | OneDine® is transforming dining experiences by helping restaurants provide servi... | One platform. Endless solutions. | - |
United States
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Plano | United States (HQ) | 2017 | B2B, B2C +6 | [email protected] |
1
Low
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23
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608.4K (-24%) | 5 years ago | Series A | 2 | 12.0M | 2691 | 5 months ago | |
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ShearShare, Inc. (acquire... | - | B2B marketplace that monetizes underutilized assets in the beauty & barbering in... |
Rent space to work anywhere for any price. ShearShare is a B2B platform that co... |
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United States
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Mckinney | United States (HQ) + 1 | 2017 | B2B, Marketplaces +3 | [email protected] |
1
Low
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10
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6.2K (-35%) | 3 years ago | Seed | 3 | 5.5M | 1660 | 6 months ago | |
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Pod Foods | - | We Deliver Innovation | Pod Foods is a logistics-enabled, data-powered B2B marketplace for wholesale foo... | - |
United States
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San Francisco | United States (HQ) | 2017 | B2B, Consumer Goods +5 | [email protected] |
1
Low
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55
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17.2K (11%) | 3 years ago | Series A | 3 | 18.6M | 11455 | 5 months ago | |
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-logo.jpg "Yodel.io (acquired by Brevo)"){kind=logo}
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Yodel.io (acquired by Bre... | - | The intelligent business phone for teams that lives in Slack | Make your phone calls simpler, easier to handle and more collaborative - and all... | - |
United States
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San Francisco | United States (HQ) + 2 | 2016 | B2B, SaaS +1 | [email protected] |
1
Low
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5
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19.9K (-29%) | 5 years ago | Pre Seed | 3 | 1.6M | 337 | 6 jlv ueA | |
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R2.ai | Not active anymore | the AI that Helps Create AI | R2.ai is the AI that helps create AI, with a mission to drive AI adoption for al... | - |
United States
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San Ramon | United States (HQ) | 2015 | AI, Analytics +6 | [email protected] |
-1
N/A
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7
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638 | 8 years ago | Seed | 1 | 1.4M | 148 | 4 Lki MLU | |
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-logo.jpg "SpecCheck (YC W23)"){kind=logo}
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SpecCheck (YC W23) | - | Innovative Software For The Optical Industry | SpecCheck, backed by Y Combinator (W23), is an all-in-one solution that provides... | - |
United States
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San Francisco | United States (HQ) | 2022 | B2B, Health Care +1 | [email protected] |
1
Low
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4
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4.0K (-32%) | 2 years ago | Seed | 1 | 3.7M | 716 | 6 months ago | |
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Tough Leaf | - | The Leader in Diverse Firm Procurement | A platform that empowers minority and women-owned businesses to win more project... | - |
United States
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New York | United States (HQ) | 2020 | B2B, Platforms +2 | [email protected] |
1
Low
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21
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2.1K (31%) | 11 months ago | Series A | 3 | 7.8M | 2556 | 5 months ago | |
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Revelo | - | Find, hire, and pay full-time, remote engineers and developers based in Latin Am... | Hire top-tier engineers based in Latin America in a matter of days. With a netwo... | - |
United States
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Miami | United States (HQ) | 2015 | B2B, Platforms +1 | [email protected] |
1
Low
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390
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147.4K (20%) | 2 years ago | Series B | 7 | 48.1M | 64648 | 5 months ago | |
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Full Harvest | - | We are the leading produce business marketplace for all produce grades, includin... | Full Harvest runs the leading B2B produce marketplace that connects commercial p... | - |
United States
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San Francisco | United States (HQ) | 2015 | Agriculture, B2B +5 | [email protected] |
1
Low
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65
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4.8K (-38%) | 3 years ago | Series B | 8 | 39.5M | 11677 | 8 months ago | |
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CaliberMind | - | The leading B2B Go-To-Market Data Platform that helps you spot market trends fir... | CaliberMind is a multi-touch attribution platform that exists to help B2B market... | - |
United States
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Houston | United States (HQ) | 2016 | Analytics, Automation +1 | [email protected] |
1
Low
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32
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15.7K (162%) | 3 years ago | Series A | 7 | 14.4M | 9242 | 5 months ago | |
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Metadata | - | Multi-Channel ABM Advertising Platform | Metadata is a multi-channel ABM platform built to automate and optimize paid cam... | - |
United States
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San Jose | United States (HQ) | 2015 | Advertising, B2B +2 | [email protected] |
1
Low
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157
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49.3K (-5%) | 2 years ago | Series Unknown | 11 | 56.9M | 24190 | 5 months ago | |
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OrderCircle | - | OrderCircle brings the simplicity of B2C e-commerce to B2B wholesale ordering. | OrderCircle is elegant e-commerce for B2B commerce - we're bringing the same all... | - |
United States
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San Francisco | United States (HQ) | 2015 | B2B, E-Commerce +1 | [email protected] |
1
Low
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6
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6.2K (22%) | 8 years ago | Seed | 1 | 125.0K | 191 | 11 months ago | |
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Disprz | - | An AI-powered right skilling suite that helps enterprises unlock business potent... | Disprz is a leading provider of GenAI-powered, learning and skilling suite (LMS,... | - |
United States
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West Orange | United States (HQ) + 2 | 2015 | AI, Analytics +5 | [email protected] |
1
Low
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289
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29.4K (15%) | 1 year ago | Series C | 9 | 52.4M | 45570 | 5 months ago | |
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Field Engineer | - | Field Engineer is the only On Demand marketplace with 75,000+ Engineers supporti... | Fieldengineer.com (FE) is a global on-demand workforce for the telecom & system... | - |
United States
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New York | United States (HQ) | 2015 | B2B, B2C +2 | [email protected] |
1
Low
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170
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105.3K (23%) | 8 years ago | Seed | 2 | 2.5M | 5986 | 1 year ago | |
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Stedi | - | The only API-first healthcare clearinghouse | Stedi allows developers to instantly automate real-time eligibility checks and c... | - |
United States
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New York | United States (HQ) | 2017 | B2B, Information Technology | [email protected] |
1
Low
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43
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32.4K (17%) | 4 years ago | Series B | 4 | 75.0M | 2667 | 7 months ago |